Skip to main content

Advertisement

Log in

Patients with spinal deformity over the age of 75: a retrospective analysis of operative versus non-operative management

  • Original Article
  • Published:
European Spine Journal Aims and scope Submit manuscript

Abstract

Purpose

The goal of the present study was to compare the outcomes of operative and non-operative patients with adult spinal deformity (ASD) over 75 years of age.

Methods

A retrospective review of a multicenter prospective adult spinal deformity database was conducted examining patients with ASD over the age of 75 years. Demographics, comorbidities, operation-related variables, complications, radiographs, and Health-related quality of life (HRQOL) measures collected included Oswestry Disability Index, Short Form-36, and Scoliosis Research Society-22 preoperatively, and at 1 and 2 years later. Minimum clinically important difference (MCID) was calculated and also compared.

Results

27 patients (12 operative, 15 non-operative) were studied. There were no significant differences (p > 0.05) between operative and non-operative patients for age, body mass-index, and comorbidities, but operative patients had worse baseline HRQOL than non-operative patients. Operative patients had a significant improvement in radiographic parameters in 2-year HRQOL, whereas non-operative patients did not (p > 0.05). Operative patients were significantly more likely to reach MCID (range 41.7–81.8 vs. 0–33.3 %, p < 0.05). In the surgical group, 9 (75 %) patients had at least 1 complication (24 total complications).

Conclusions

In the largest series to date comparing operative and non-operative management of adult spinal deformity in elderly patients greater than 75 years of age, reconstructive surgery provides significant improvements in pain and disability over a 2-year period. Furthermore, operative patients were more likely to reach MCID than non-operative patients. When counseling elderly patients with ASD, such data may be helpful in the decision-making process regarding treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Pekmezci M, Berven SH, Hu SS, Deviren V (2009) The factors that play a role in the decision-making process of adult deformity patients. Spine (Phila Pa 1976) 34:813–817. doi:10.1097/BRS.0b013e3181851ba6

    Article  Google Scholar 

  2. Aebi M (2005) The adult scoliosis. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 14:925–948. doi:10.1007/s00586-005-1053-9

    Article  Google Scholar 

  3. Kim YJ, Bridwell KH, Lenke LG, Rinella AS, Edwards C 2nd (2005) Pseudarthrosis in primary fusions for adult idiopathic scoliosis: incidence, risk factors, and outcome analysis. Spine (Phila Pa 1976) 30:468–474

    Article  Google Scholar 

  4. Lippman CR, Spence CA, Youssef AS, Cahill DW (2003) Correction of adult scoliosis via a posterior-only approach. Neurosurg Focus 14:e5

    Article  PubMed  Google Scholar 

  5. Takahashi S, Delecrin J, Passuti N (2002) Surgical treatment of idiopathic scoliosis in adults: an age-related analysis of outcome. Spine (Phila Pa 1976) 27:1742–1748

    Article  Google Scholar 

  6. Oldridge NB, Yuan Z, Stoll JE, Rimm AR (1994) Lumbar spine surgery and mortality among Medicare beneficiaries, 1986. Am J Public Health 84:1292–1298

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Raffo CS, Lauerman WC (2006) Predicting morbidity and mortality of lumbar spine arthrodesis in patients in their ninth decade. Spine (Phila Pa 1976) 31:99–103

    Article  Google Scholar 

  8. Schoenfeld AJ, Ochoa LM, Bader JO, Belmont PJ Jr (2011) Risk factors for immediate postoperative complications and mortality following spine surgery: a study of 3475 patients from the National Surgical Quality Improvement Program. J Bone Joint Surg Am 93:1577–1582. doi:10.2106/JBJS.J.01048

    PubMed  Google Scholar 

  9. Roussouly P, Labelle H, Rouissi J, Bodin A (2013) Pre- and post-operative sagittal balance in idiopathic scoliosis: a comparison over the ages of two cohorts of 132 adolescents and 52 adults. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 22(Suppl 2):S203–S215. doi:10.1007/s00586-012-2571-x

    Article  Google Scholar 

  10. Bridwell KH, Glassman S, Horton W, Shaffrey C, Schwab F, Zebala LP, Lenke LG, Hilton JF, Shainline M, Baldus C, Wootten D (2009) Does treatment (nonoperative and operative) improve the two-year quality of life in patients with adult symptomatic lumbar scoliosis: a prospective multicenter evidence-based medicine study. Spine (Phila Pa 1976) 34:2171–2178. doi:10.1097/BRS.0b013e3181a8fdc8

    Article  Google Scholar 

  11. Smith JS, Shaffrey CI, Glassman SD, Berven SH, Schwab FJ, Hamill CL, Horton WC, Ondra SL, Sansur CA, Bridwell KH, Spinal Deformity Study G (2011) Risk-benefit assessment of surgery for adult scoliosis: an analysis based on patient age. Spine (Phila Pa 1976) 36:817–824. doi:10.1097/BRS.0b013e3181e21783

    Article  Google Scholar 

  12. Champain S, Benchikh K, Nogier A, Mazel C, Guise JD, Skalli W (2006) Validation of new clinical quantitative analysis software applicable in spine orthopaedic studies. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 15:982–991. doi:10.1007/s00586-005-0927-1

    Article  CAS  Google Scholar 

  13. Rillardon L, Levassor N, Guigui P, Wodecki P, Cardinne L, Templier A, Skalli W (2003) Validation of a tool to measure pelvic and spinal parameters of sagittal balance. Rev Chir Orthop Reparatrice Appar Mot 89:218–227

    CAS  PubMed  Google Scholar 

  14. O’Brien MF, Kuklo TR, Blanke KM, Lenke LG (eds) (2005) Spinal Deformity Study Group Radiographic Measurement Manual. Medtronic Sofamor Danek, Inc., Minneapolis, MN

  15. Roussouly P, Pinheiro-Franco JL (2011) Sagittal parameters of the spine: biomechanical approach. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 20(Suppl 5):578–585. doi:10.1007/s00586-011-1924-1

    Article  Google Scholar 

  16. Legaye J, Duval-Beaupere G, Hecquet J, Marty C (1998) Pelvic incidence: a fundamental pelvic parameter for three-dimensional regulation of spinal sagittal curves. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 7:99–103

    Article  CAS  Google Scholar 

  17. Roussouly P, Pinheiro-Franco JL (2011) Biomechanical analysis of the spino-pelvic organization and adaptation in pathology. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 20(Suppl 5):609–618. doi:10.1007/s00586-011-1928-x

    Article  Google Scholar 

  18. Schwab F, Ungar B, Blondel B, Buchowski J, Coe J, Deinlein D, DeWald C, Mehdian H, Shaffrey C, Tribus C, Lafage V (2012) Scoliosis Research Society-Schwab adult spinal deformity classification: a validation study. Spine 37:1077–1082. doi:10.1097/BRS.0b013e31823e15e2

    Article  PubMed  Google Scholar 

  19. Blondel B, Schwab F, Ungar B, Smith J, Bridwell K, Glassman S, Shaffrey C, Farcy JP, Lafage V (2012) Impact of magnitude and percentage of global sagittal plane correction on health-related quality of life at 2-years follow-up. Neurosurgery 71:341–348. doi:10.1227/NEU.0b013e31825d20c0 (discussion 348)

    Article  PubMed  Google Scholar 

  20. Glassman SD, Copay AG, Berven SH, Polly DW, Subach BR, Carreon LY (2008) Defining substantial clinical benefit following lumbar spine arthrodesis. J Bone Joint Surg Am 90:1839–1847. doi:10.2106/JBJS.G.01095

    Article  PubMed  Google Scholar 

  21. Carreon LY, Sanders JO, Diab M, Sucato DJ, Sturm PF, Glassman SD, Spinal Deformity Study G (2010) The minimum clinically important difference in Scoliosis Research Society-22 Appearance, Activity, And Pain domains after surgical correction of adolescent idiopathic scoliosis. Spine 35:2079–2083. doi:10.1097/BRS.0b013e3181c61fd7

    Article  PubMed  Google Scholar 

  22. Copay AG, Glassman SD, Subach BR, Berven S, Schuler TC, Carreon LY (2008) Minimum clinically important difference in lumbar spine surgery patients: a choice of methods using the Oswestry Disability Index, Medical Outcomes Study questionnaire Short Form 36, and pain scales. Spine J Off J North Am Spine Soc 8:968–974. doi:10.1016/j.spinee.2007.11.006

    Article  Google Scholar 

  23. Baldus C, Bridwell K, Harrast J, Shaffrey C, Ondra S, Lenke L, Schwab F, Mardjetko S, Glassman S, Edwards C 2nd, Lowe T, Horton W, Polly D Jr (2011) The Scoliosis Research Society Health-Related Quality of Life (SRS-30) age-gender normative data: an analysis of 1346 adult subjects unaffected by scoliosis. Spine (Phila Pa 1976) 36:1154–1162. doi:10.1097/BRS.0b013e3181fc8f98

    Article  Google Scholar 

  24. McCarthy I, O’Brien M, Ames C, Robinson C, Errico T, Polly DW Jr, Hostin R, International Spine Study G (2014) Incremental cost-effectiveness of adult spinal deformity surgery: observed quality-adjusted life years with surgery compared with predicted quality-adjusted life years without surgery. Neurosurg Focus 36:E3. doi:10.3171/2014.3.FOCUS1415

    Article  PubMed  Google Scholar 

  25. Schwab F, Dubey A, Gamez L, El Fegoun AB, Hwang K, Pagala M, Farcy JP (2005) Adult scoliosis: prevalence, SF-36, and nutritional parameters in an elderly volunteer population. Spine (Phila Pa 1976) 30:1082–1085

    Article  Google Scholar 

  26. Bradford DS (1988) Adult scoliosis. Current concepts of treatment. Clin Orthop Relat Res (229):70–87

  27. Li G, Passias P, Kozanek M, Fu E, Wang S, Xia Q, Li G, Rand FE, Wood KB (2009) Adult scoliosis in patients over sixty-five years of age: outcomes of operative versus nonoperative treatment at a minimum two-year follow-up. Spine (Phila Pa 1976) 34:2165–2170. doi:10.1097/BRS.0b013e3181b3ff0c

    Article  Google Scholar 

  28. Liu S, Schwab F, Smith JS, Klineberg E, Ames CP, Mundis G, Hostin R, Kebaish K, Deviren V, Gupta M, Boachie-Adjei O, Hart RA, Bess S, Lafage V (2014) Likelihood of reaching minimal clinically important difference in adult spinal deformity: a comparison of operative and nonoperative treatment. Ochsner J 14:67–77

    PubMed  PubMed Central  Google Scholar 

  29. Smith JS, Shaffrey CI, Berven S, Glassman S, Hamill C, Horton W, Ondra S, Schwab F, Shainline M, Fu KM, Bridwell K, Spinal Deformity Study G (2009) Operative versus nonoperative treatment of leg pain in adults with scoliosis: a retrospective review of a prospective multicenter database with two-year follow-up. Spine (Phila Pa 1976) 34:1693–1698. doi:10.1097/BRS.0b013e3181ac5fcd

    Article  Google Scholar 

  30. Smith JS, Shaffrey CI, Berven S, Glassman S, Hamill C, Horton W, Ondra S, Schwab F, Shainline M, Fu KM, Bridwell K, Spinal Deformity Study G (2009) Improvement of back pain with operative and nonoperative treatment in adults with scoliosis. Neurosurgery 65:86–93. doi:10.1227/01.NEU.0000347005.35282.6C (discussion 93–84)

    Article  PubMed  Google Scholar 

  31. Terran J, Schwab F, Shaffrey CI, Smith JS, Devos P, Ames CP, Fu KM, Burton D, Hostin R, Klineberg E, Gupta M, Deviren V, Mundis G, Hart R, Bess S, Lafage V, International Spine Study G (2013) The SRS-Schwab adult spinal deformity classification: assessment and clinical correlations based on a prospective operative and nonoperative cohort. Neurosurgery 73:559–568. doi:10.1227/NEU.0000000000000012

    Article  PubMed  Google Scholar 

  32. Acosta FL Jr, McClendon J Jr, O’Shaughnessy BA, Koller H, Neal CJ, Meier O, Ames CP, Koski TR, Ondra SL (2011) Morbidity and mortality after spinal deformity surgery in patients 75 years and older: complications and predictive factors. J Neurosurg Spine 15:667–674. doi:10.3171/2011.7.SPINE10640

    Article  PubMed  Google Scholar 

  33. Hassanzadeh H, Jain A, El Dafrawy MH, Ain MC, Mesfin A, Skolasky RL, Kebaish KM (2012) Three-column osteotomies in the treatment of spinal deformity in adult patients 60 years old and older: outcome and complications. Spine (Phila Pa 1976) 38:726–731

    Article  Google Scholar 

  34. Daubs MD, Lenke LG, Cheh G, Stobbs G, Bridwell KH (2007) Adult spinal deformity surgery: complications and outcomes in patients over age 60. Spine (Phila Pa 1976) 32:2238–2244. doi:10.1097/BRS.0b013e31814cf24a

    Article  Google Scholar 

  35. Smith JS, Sansur CA, Donaldson WF 3rd, Perra JH, Mudiyam R, Choma TJ, Zeller RD, Knapp DR Jr, Noordeen HH, Berven SH, Goytan MJ, Boachie-Adjei O, Shaffrey CI (2011) Short-term morbidity and mortality associated with correction of thoracolumbar fixed sagittal plane deformity: a report from the Scoliosis Research Society Morbidity and Mortality Committee. Spine 36:958–964. doi:10.1097/BRS.0b013e3181eabb26

    Article  PubMed  Google Scholar 

  36. Barrey C, Roussouly P, Le Huec JC, D’Acunzi G, Perrin G (2013) Compensatory mechanisms contributing to keep the sagittal balance of the spine. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 22(Suppl 6):S834–S841. doi:10.1007/s00586-013-3030-z

    Article  Google Scholar 

  37. Barrey C, Roussouly P, Perrin G, Le Huec JC (2011) Sagittal balance disorders in severe degenerative spine. Can we identify the compensatory mechanisms? Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 20(Suppl 5):626–633. doi:10.1007/s00586-011-1930-3

    Article  Google Scholar 

Download references

Acknowledgments

Funding for the International Spine Study Group Foundation, through which this study was conducted, is funded through research grants from DePuy Spine and individual donations.

Conflict of interest

None of the authors have a conflict of interest with this manuscript.

Author information

Authors and Affiliations

Authors

Consortia

Corresponding author

Correspondence to Daniel M. Sciubba.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sciubba, D.M., Scheer, J.K., Yurter, A. et al. Patients with spinal deformity over the age of 75: a retrospective analysis of operative versus non-operative management. Eur Spine J 25, 2433–2441 (2016). https://doi.org/10.1007/s00586-015-3759-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00586-015-3759-7

Keywords

Navigation