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PMMA microfluidic chip fabrication using laser ablation and low temperature bonding with OCA film and LOCA

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Abstract

A new PMMA microfluidic chip fabrication method by combining laser ablation technology with low-temperature bonding using optically clear adhesive (OCA) film and liquid optically clear adhesive (LOCA) was presented in this paper. The deformation and clogging issues of the microfluidic channel were well solved. The effective bonding area ratio of microfluidic chips could be greatly improved by adjusting bonding temperature and bonding time. The crevices around the microchannels were effectively eliminated by coating treatment of LOCA. The bonding strength and waterproof of PMMA microfluidic chips coating with/without LOCA were also evaluated in this paper.

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Acknowledgments

This work was supported in part by following foundations: (1) National Natural Science Foundation of China (Grant No. 21105076, Grant No. 81372358, Grant No. 51303140 and Grant No. 51302196), (2) Foundation of Education Bureau of Hubei Province, China (Grant No. D20121705), (3) Science Technology Foundation of Hubei Province, China (Grant No. 2011BAB038), (4) Natural Science Foundation of Hubei Province, China (Grant No. 2014CF029), (5) Colleges of Hubei Province Outstanding Youth Science and Technology Innovation Team (Grant No. T201305).

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Authors and Affiliations

  1. College of Electronic and Electrical Engineering, Textile Industry Chain Collaboration Generic Technology Innovation Center, and Textile Materials and Advanced Processing Technology Hubei Province and Ministry State Key Laboratory Breeding Base, Wuhan Textile University, Wuhan, 430200, Hubei, People’s Republic of China

    Kan Liu, Jianzhen Xiang, Zhao Ai, Shoukun Zhang, Yi Fang, Ting Chen, Qiongwei Zhou, Songzhan Li, Shengxiang Wang & Nangang Zhang

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  1. Kan Liu
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  2. Jianzhen Xiang
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  3. Zhao Ai
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  4. Shoukun Zhang
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  5. Yi Fang
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  6. Ting Chen
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  7. Qiongwei Zhou
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  8. Songzhan Li
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  9. Shengxiang Wang
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  10. Nangang Zhang
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Correspondence to Nangang Zhang.

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Liu, K., Xiang, J., Ai, Z. et al. PMMA microfluidic chip fabrication using laser ablation and low temperature bonding with OCA film and LOCA. Microsyst Technol 23, 1937–1942 (2017). https://doi.org/10.1007/s00542-016-2924-1

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  • DOI: https://doi.org/10.1007/s00542-016-2924-1

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