Neurological prognosis of 6 cases after chest compression during general anesthesia
Data on the outcomes after chest compression (CC) of patients who are under general anesthesia (GA) are limited. The present study aimed to evaluate the neurological outcomes in patients who received CC while under GA.
The patients who received CC while under GA, between 2010 and 2015, in Kyoto Medical Center were surveyed retrospectively. The primary outcome was poor neurologic function or death, as defined by a cerebral performance category score (CPC) score of 3–5 on day 28.
Six patients received CC while under GA, and four patients had poor neurological outcomes with a CPC score of 4 or 5 on day 28. All these patients required emergency operation because of their primary disease.
Even if the patients were monitored and immediately managed under GA, ineffective management of preoperative conditions tended to result in the poor neurological prognosis.
KeywordsChest compression General anesthesia Neurological prognosis
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 2.Ramachandran SK, Mhyre J, Kheterpal S, Christensen RE, Tallman K, Morris M, Chan PS. Predictors of survival from perioperative cardiopulmonary arrests: a retrospective analysis of 2524 events from the get with the guidelines-resuscitation registry. Anesthesiology. 2013;119:1322–39.CrossRefPubMedGoogle Scholar
- 3.Fukuda T, Ohashi-Fukuda N, Matsubara T, Doi K, Kitsuta Y, Nakajima S, Yahagi N. Association of initial rhythm with neurologically favorable survival in non-shockable out-of-hospital cardiac arrest without a bystander witness or bystander cardiopulmonary resuscitation. Eur J Intern Med. 2016;30:61–7.CrossRefPubMedGoogle Scholar
- 6.Sun M, Deng B, Zhao X, Gao C, Yang L, Zhao H, Yu D, Zhang F, Xu L, Chen L, Sun X. Isoflurane preconditioning provides neuroprotection against stroke by regulating the expression of the TLR4 signalling pathway to alleviate microglial activation. Sci Rep. 2015. https://doi.org/10.1038/srep11445.Google Scholar
- 7.Constant AL, Montlahuc C, Grimaldi D, Pichon N, Mongardon N, Bordenave L, Soummer A, Sauneuf B, Ricome S, Misset B, Schnell D, Dubuisson E, Brunet J, Lasocki S, Cronier P, Bouhemad B, Loriferne JF, Begot E, Vandenbunder B, Dhonneur G, Bedos JP, Jullien P, Resche-Rigon M, Legriel S. Predictors of functional outcome after intraoperative cardiac arrest. Anesthesiology. 2014;121:482–91.CrossRefPubMedGoogle Scholar