Abstract
Purpose
To assess the effectiveness of healthy lifestyle–based interventions in lung cancer survivors.
Methods
We performed a literature search using PubMed, Web of Science, and Science Direct (last search March 2022). Quality assessment and risk of bias were assessed using the Downs and Black scale and the Cochrane tool. A systematic review and meta-analysis of randomized controlled trials were performed. We included controlled trials testing the effect of healthy lifestyle–based interventions in lung cancer survivors versus a control intervention where lung cancer patients had no treatment, were receiving the usual care, or had not an active role in the intervention. The data were pooled and a meta-analysis was completed for quality of life, psychological distress, and cancer-related symptoms.
Results
We selected 14 studies, which included 1519 patients with lung cancer. The treatment status of these patients was heterogeneous. Healthy lifestyle programs were applied isolated or in combination with usual care in most of the studies. The components of the healthy lifestyle programs were also heterogeneous. Results showed significant differences in favor of healthy lifestyle–based interventions in comparison to the control group for quality of life (p = 0.01), psychological distress (p = 0.05), and cancer-related symptoms (p = 0.03).
Conclusions
The findings indicated a beneficial effect of healthy lifestyle–based interventions for improving quality of life, psychological distress, and cancer-related symptoms in lung cancer patients. However, this review could not show any conclusion about the better treatment moment to apply healthy lifestyle–based interventions.
Review registration
PROSPERO Identifier: CRD42021292152.
Review registration date
19/12/2021.
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Data availability
Not applicable.
Code availability
Not applicable.
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Funding
Heredia-Ciuró Alejandro has received financial support through a FPU (“Formación Profesorado Universitario”) grant (FPU:20/01670) of the Spanish Ministry of Education. The author Calvache-Mateo Andrés has received financial support through a FPU (“Formación Profesorado Universitario”) grant (FPU:19/02609) of the Spanish Ministry of Education.
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The author Valenza Marie Carmen had the idea for the article and full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Heredia-Ciuró Alejandro and Martín-Núñez Javier had full access to all the data in the study and takes responsibility for performing the literature search and data analysis. López-López José Antonio, López-López Laura, Granados-Santiago María, and Calvache-Mateo Andrés contributed substantially to draft and critically revise the work, and the writing of the manuscript.
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Appendix. Search strategy
Appendix. Search strategy
Pubmed
(neoplas*[Title/Abstract]) OR (metastat*[Title/Abstract])) OR (cancer*[Title/Abstract])) OR (carcino[Title/Abstract])) OR (carcinoma*[Title/Abstract])) OR (onco*[Title/Abstract])) OR (tumor*[Title/Abstract])) OR (tumour*[Title/Abstract])) OR (malignan*[Title/Abstract])) AND (Lung[Title/Abstract])) OR (Lungs[Title/Abstract])) AND (self care[Title/Abstract])) OR (self-care[Title/Abstract])) OR (self manage[Title/Abstract])) OR (self-manage[Title/Abstract])) OR (self efficacy[Title/Abstract])) OR (self-efficacy[Title/Abstract])) OR (home base[Title/Abstract])) OR (home-base[Title/Abstract])) OR (health education[Title/Abstract])) OR (patient education[Title/Abstract])) OR (patient participation[Title/Abstract])) OR (health communication[Title/Abstract])) OR (health promotion[Title/Abstract])) OR (self concept[Title/Abstract])) OR (self-control[Title/Abstract])) OR (self concept[MeSH Terms])) OR (self-regulation[Title/Abstract])) OR (patient autonomy[Title/Abstract])) OR (patient compliance[MeSH Terms])) OR (health behavior[MeSH Terms])) OR (health attitude[Title/Abstract])) OR (illness attitude[Title/Abstract])) OR (patient attitude[Title/Abstract])) OR (choice behavior[MeSH Terms])) OR (illness behavior[MeSH Terms])) OR (Self-management[Title/Abstract])) OR (adaptation, psychological[MeSH Terms])) OR (adjustment disorders[MeSH Terms])) OR (disease management[MeSH Terms])) OR (Adjustment[Title/Abstract]).
Web of Science
(neoplas* OR metastat* OR cancer* OR carcino* OR carcinoma* OR onco* OR tumor* OR tumour* OR malignan*) AND (“Lung” OR “Lungs”) AND (“self care” OR “self-care” OR “self manage” OR “self-manage” OR “self efficacy” OR “self-efficacy” OR “home base” OR “home-base” OR “health education” OR “patient education” OR “patient participation” OR “health communication” OR “health promotion” OR “self concept” OR “Self-control” OR “Self-regulation” OR Patient autonomy* OR “health behavior” OR “Health attitude” OR “Illness attitude” OR Patient attitude* OR “Self management” OR Adjustment*) AND (RCT OR Randomized Controlled Trial).
Science Direct
(*neoplas OR *metastat OR *cancer OR *carcino OR *carcinoma OR *onco OR *tumor OR *tumour OR *malignan) AND (“Lung” OR “Lungs”) AND (“self care” OR “self-care” OR “self manage” OR “self-manage” OR “self efficacy” OR “self-efficacy” OR “home base” OR “home-base” OR “health education” OR “patient education” OR “patient participation” OR “health communication” OR “health promotion” OR “self concept” OR “Self-control” OR “Self-regulation” OR *Patient autonomy OR “health behavior” OR “Health attitude” OR “Illness attitude” OR *Patient attitude OR “Self management” OR *Adjustment) AND (RCT OR Randomized Controlled Trial).
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Heredia-Ciuró, A., Martín-Núñez, J., López-López, J.A. et al. Effectiveness of healthy lifestyle–based interventions in lung cancer survivors: a systematic review and meta-analysis. Support Care Cancer 31, 71 (2023). https://doi.org/10.1007/s00520-022-07542-0
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DOI: https://doi.org/10.1007/s00520-022-07542-0