Assessment of health-related quality of life among parents of children with solid tumors in Serbia



The aim of the study was to assess health-related quality of life (HRQoL) and contributing factors among parents of children with solid tumors in Serbia.


The cross-sectional study included 51 parents of children treated for different solid tumors at the Institute of Oncology and Radiology of Serbia. Parents filled out validated Serbian version of SF-36 questionnaire. Hierarchical multiple regression analysis was conducted to identify predictors of total score of SF-36.


Almost all parents (94.1%) were mothers and average age was 38.6 ± 6.7 years. Majority of children had brain tumors (43.1%), followed by bone tumors (37.3%). The hierarchical regression analysis showed that socio-demographic characteristics explained 26% of the variance (p > 0.05) of the total score of SF-36. Addition of quality of life of children assessed by parents in the second model caused an increase of 21% in the variance explained (p < 0.05). After adding the Beck Depression Inventory score in the third block, an additional 18% of the variance in total score was explained (p < 0.05).


This study showed that HRQoL measured by SF-36 in parents of children with cancer is strongly influenced by depression and quality of life of children assessed by parents.

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This investigation was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Grant No. 175087).

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Corresponding author

Correspondence to Tatjana Pekmezovic.

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Following detailed information about the aims of the study, all parents signed inform consent for participation in the research and all of them accepted to take a part in the investigation. Study was approved by the Ethical Commission of the Faculty of Medicine, University of Belgrade.

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The authors declare that they have no conflict of interest.

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Ilic, V., Nikitovic, M., Maric, G. et al. Assessment of health-related quality of life among parents of children with solid tumors in Serbia. Support Care Cancer 28, 5109–5115 (2020).

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  • Health-related quality of life
  • Childhood cancer
  • Parents
  • Hierarchical regression analysis