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Leung J, Crook M (2019) Disorders of phosphate metabolism. J Clin Pathol 72:741–747
Carfagna F, Del Vecchio L, Pontoriero G, Locatelli F (2018) Current and potential treatment options for hyperphosphatemia. Expert Opin Drug Saf 17:597–607
Messa P, Alfieri CM (2018) Secondary and tertiary hyperparathyroidism. Front Horm Res 51:91–108. https://doi.org/10.1159/000491041
Whyte MP (2017) Hypophosphatasia: an overview for 2017. Bone 102:15–25. https://doi.org/10.1016/j.bone.2017.02.011
Di Rocco F, Baujat G, Cormier-Daire V, Rothenbuhler A, Linglart A (2017) Craniosynostosis and hypophosphatasia. Arch Pediatr 24:5S89–5S92. https://doi.org/10.1016/S0929-693X(18)30022-8
Taketani T, Onigata K, Kobayashi H, Mushimoto Y, Fukuda S, Yamaguchi S (2014) Clinical and genetic aspects of hypophosphatasia in Japanese patients. Arch Dis Child 99:211–215. https://doi.org/10.1136/archdischild-2013-305037
Whyte MP, Greenberg CR, Salman NJ, Bober MB, McAlister WH, Wenkert D, Van Sickle BJ, Simmons JH, Edgar TS, Bauer ML, Hamdan MA, Bishop N, Lutz RE, McGinn M, Craig S, Moore JN, Taylor JW, Cleveland RH, Cranley WR, Lim R, Thacher TD, Mayhew JE, Downs M, Millán JL, Skrinar AM, Crine P, Landy H (2012) Enzyme-replacement therapy in life-threatening hypophosphatasia. N Engl J Med 366:904–913. https://doi.org/10.1056/NEJMoa1106173
Whyte MP, Simmons JH, Moseley S, Fujita KP, Bishop N, Salman NJ, Taylor J, Phillips D, McGinn M, McAlister WH (2019) Asfotase alfa for infants and young children with hypophosphatasia: 7 year outcomes of a single-arm, open-label, phase 2 extension trial. Lancet Diabetes Endocrinol 7:93–105. https://doi.org/10.1016/S2213-8587(18)30307-3
Kishnani PS, Rush ET, Arundel P, Bishop N, Dahir K, Fraser W, Harmatz P, Linglart A, Munns CF, Nunes ME, Saal HM, Seefried L, Ozono K (2017) Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa. Mol Genet Metab 122(1–2):4–17. https://doi.org/10.1016/j.ymgme.2017.07.010
Whyte MP (2017) Hypophosphatasia: an overview for 2017. Bone. 102:15–25. https://doi.org/10.1016/j.bone.2017.02.011
Whyte MP, Zhang F, Wenkert D, McAlister WH, Mack KE, Benigno MC, Coburn SP, Wagy S, Griffin DM, Ericson KL, Mumm S (2015) Hypophosphatasia: validation and expansion of the clinical nosology for children from 25years experience with 173 pediatric patients. Bone 75:229–239. https://doi.org/10.1016/j.bone.2015.02.022
Sağlam H, Erdöl Ş, Dorum S (2017) Clinical and genetic findings of Turkish hypophosphatasia cases. JCRPE J Clin Res Pediatr Endocrinol 9:229–236. https://doi.org/10.4274/jcrpe.4549
Baujat G, Michot C, Le Quan Sang KH, Cormier-Daire V (2017) Perinatal and infantile hypophosphatasia: clinical features and treatment. Arch Pediatr 24:5S61–5S65. https://doi.org/10.1016/S0929-693X(18)30016-2
Bacchetta J (2017) Renal impairment in hypophosphatasia. Arch Pediatr 24:5S93–5S95. https://doi.org/10.1016/S0929-693X(18)30023-X
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Özler, O., Mutlu, G.Y., Taşdemir, M. et al. An 8-month-old infant with hypercalcemia and hyperphosphatemia—Answers. Pediatr Nephrol (2020). https://doi.org/10.1007/s00467-020-04666-5
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