IPDN-China promotes the development of pediatric dialysis in China



In mainland China, dialysis for children with end-stage renal disease (ESRD) was not introduced until the 1980s. To describe the development of pediatric dialysis in different regions of China, a national pediatric dialysis network, namely, International Pediatric Dialysis Network-China (IPDN-China) (www.pedpd.org.cn), was launched in 2012.


Original and updated information from the renal centers registered with the IPDN-China was collected between 2012 and 2016 from two sources, namely, the registry and the survey, and demographic features were analyzed.


Due to promotion by the IPDN-China, the number of registered renal centers increased from 12 to 39 between 2012 and 2016, with a significant increase in the coverage of the Chinese administrative divisions (from 26.5 to 67.6%) (p < 0.01); and the coverage of the pediatric (0~14 years old) population increased to nearly 90% in 2016. The distribution of renal centers indicated that East China had the highest average number of registered centers per million population (pmp) 0~14-year-old age group. Seventeen relatively large dialysis centers were distributed across 14 divisions. Various modalities of renal replacement therapy (RRT) were available in most centers. The IPDN-China has promoted collaborations between dieticians, psychologists, and social workers on dialysis teams to provide better service to children with ESRD and their families. The proportion of centers with all three types of paramedic support (i.e., dieticians, psychologists, and social workers) as well as the proportion of centers with a partial paramedic team significantly increased between 2012 (25.0%) and 2016 (69.2%) (p < 0.05). In terms of the point prevalent cases of patients (aged < 18 years), data from the survey of 39 registered centers revealed that the number of children with ESRD who were on RRT was 578 (49% received a kidney transplant) at the end of 2016, which was more than that reported in previous surveys. Data from the registry showed that 349 dialysis patients had been enrolled as of the end of 2016. The median age at RRT start was 9.5 years, and the leading cause of ESRD was congenital abnormalities of the kidney and urinary tract (CAKUT).


The IPDN-China has helped to promote the development of pediatric dialysis for ESRD in China by improving the organization of care for dialysis patients and increasing the availability and the quality of RRT for patients who need it. To improve knowledge about the epidemiology and outcomes of pediatric RRT around the country, a sustained effort needs to be made by the IPDN-China to increase the enrollment of dialysis patients and increase the number of registered centers in the future.

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We sincerely appreciate Prof. Franz Schaefer and his colleagues for their kind help on the creation of the online registry platform of the IPDN-China.


This study received funding from the Key Developing Discipline of Shanghai Municipal Commission of Health and Family Planning (Pediatrics), 2016ZB0101.

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Correspondence to Qian Shen or Ying Shen or Hong Xu.

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The study protocol was approved by the ethical committees/institutional review boards as required at each participating center. Written parental consent, as well as assent from patients when appropriate was obtained.

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The authors declare that they have no conflict of interest.

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Zhai, Y., Liu, X., Yang, Q. et al. IPDN-China promotes the development of pediatric dialysis in China. Pediatr Nephrol (2020). https://doi.org/10.1007/s00467-020-04630-3

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  • IPDN-China
  • Registry
  • ESRD
  • Pediatric dialysis
  • Renal replacement therapy