Steroid-responsive nephrotic syndrome in a child with juvenile idiopathic arthritis

Abstract

Renal disease is rare in children with juvenile idiopathic arthritis, although a number of associated nephropathies have been described, including mesangial glomerulonephritis. We report the presence of mesangial glomerulonephritis, revealed by a nephrotic syndrome, in a paediatric patient with juvenile idiopathic arthritis. Short-term steroid treatment induced a rapid remission of the nephrotic syndrome, but the presence of anti-nuclear antibodies, 1:320 in a homogeneous pattern, irregular deposits of C1q in a renal biopsy, and a mother with episodes of cutaneous lupus suggested an uncertain renal evolution for this infant.

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Correspondence to Flavio Bandin.

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Bandin, F., Merhenberger, M., Modesto, A. et al. Steroid-responsive nephrotic syndrome in a child with juvenile idiopathic arthritis. Pediatr Nephrol 23, 651–654 (2008). https://doi.org/10.1007/s00467-007-0678-9

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Keywords

  • Juvenile idiopathic arthritis
  • Mesangial glomerulonephritis
  • Nephrotic syndrome
  • C1q deposits