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Endoscopic gastrojejunostomy revision is more effective than medical management alone to address weight regain after RYGB

  • Endoluminal Surgery
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Abstract

Background

Weight regain after bariatric roux-en-y gastric bypass affects up to 30% of individuals. Revisional surgery is risky, and is typically avoided in favor of dietary and psychological management. Endoscopic gastrojejunostomy revision is a low-morbidity, outpatient procedure that may be more effective than medical management alone for regain after gastric bypass.

Methods

Two patient cohorts were retrospectively assembled. Both groups had gastric bypass, regained weight, and were cleared for revision by their surgeon, dietician, and psychologist. The revision group underwent the procedure, and the no-revision group did not, typically due to insurance issues. Weights from pre-bypass to 2 years post-revision, obesity-related comorbidities, and intraoperative factors were collected and analyzed.

Results

There were 41 patients included in the revision group and 14 in the no-revision group. Up to the time of revision procedure, body mass index, and % excess weight loss between groups were similar. After revision, the groups diverged over a 2-year period, with improvement seen in the revision group and worsening in the no-revision group. The revision group showed overall improvement in comorbidities compared to the no-revision group. Analysis of intraoperative factors suggests that gastric pouch restriction in addition to stoma diameter reduction may promote weight loss.

Conclusions

In this retrospective study, endoscopic revision provided significantly greater weight loss compared to medical management alone. Results show that revision can help resolve obesity-related comorbidities. Analysis of intraoperative factors suggests that pouch reduction at time of stoma revision may improve weight loss.

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References

  1. Buchwald H, Avidor Y, Braunwald E et al (2004) Bariatric surgery: a systematic review and meta-analysis. JAMA 292:1724–1737

    Article  CAS  PubMed  Google Scholar 

  2. Obeid NR, Malick W, Concors SJ, Fielding GA, Kurian MS, Ren-Fielding CJ (2016) Long-term outcomes after Roux-en-Y gastric bypass: 10- to 13-year data. Surg Obes Relat Dis 12(1):11–20. https://doi.org/10.1016/j.soard.2015.04.011

    Article  PubMed  Google Scholar 

  3. Schwartz RW, Stodel WE, Simpson WS et al (1988) Gastric bypass revision: lessons learned from 920 cases. Surgery 104:806–812

    CAS  PubMed  Google Scholar 

  4. Ponce J, Nguyen NT, Hutter M, Sudan R, Morton JM (2015) American society for metabolic and bariatric surgery estimation of bariatric surgery procedures in the United States, 2011–2014. Surg Obes Relat Dis 11(6):1199–1200

    Article  PubMed  Google Scholar 

  5. Meguid MM, Glade MJ, Middleton FA (2008) Weight regain after Roux-en-Y: a significant 20% complication related to PYY. Nutrition 24:832–842

    Article  CAS  PubMed  Google Scholar 

  6. Christou NV, Look D, Maclean LD (2006) Weight gain after short- and long limb gastric bypass in patients followed for longer than 10 years. Ann Surg 244:734–740

    Article  PubMed  PubMed Central  Google Scholar 

  7. Faria SL, Kelly E, Faria OP (2009) Energy expenditure and weight regain in patients submitted to Roux-en-Y gastric bypass. Obes Surg 19:856–859

    Article  PubMed  Google Scholar 

  8. Brolin RE (2002) Bariatric surgery and long-term control of morbid obesity. JAMA 288:2793–2796

    Article  PubMed  Google Scholar 

  9. Odom J, Zalesin KC, Washington TL et al (2010) Behavioral predictors of weight regain after bariatric surgery. Obes Surg 20:349–356

    Article  PubMed  Google Scholar 

  10. DiGiorgi M, Rosen DJ, Choi JJ et al (2010) Re-emergence of diabetes after gastric bypass in patients with mid- to long-term follow-up. Surg Obes Relat Dis 6:249–253

    Article  PubMed  Google Scholar 

  11. Chikunguwo SM, Wolfe LG, Dodson P et al (2010) Analysis of factors associated with durable remission of diabetes after Roux-en-Y gastric bypass. Surg Obes Relat Dis 6:254–259

    Article  PubMed  Google Scholar 

  12. Abu Dayyeh BK, Lautz DB, Thompson CC (2011) Gastrojejunal stoma diameter predicts weight regain after Roux-en-Y gastric bypass. Clin Gastroenterol Hepatol 9:228–233

    Article  PubMed  Google Scholar 

  13. Thompson CC, Chand B, Chen YK, Demarco DC, Miller L, Schweitzer M, Rothstein RI, Lautz DB, Slattery J, Ryan MB, Brethauer S, Schauer P, Mitchell MC, Starpoli A, Haber GB, Catalano MF, Edmundowicz S, Fagnant AM, Kaplan LM, Roslin MS (2013) Endoscopic suturing for transoral outlet reduction increases weight loss after Roux-en-Y gastric bypass surgery. Gastroenterology 145(1):129–137. https://doi.org/10.1053/j.gastro.2013.04.002

    Article  PubMed  Google Scholar 

  14. Gagner M, Gentileschi P, de Csepel J, Kini S, Patterson E, Inabnet WB, Herron D, Pomp A (2002) Laparoscopic reoperative bariatric surgery: experience from 27 consecutive patients. Obes Surg 12(2):254–260

    Article  PubMed  Google Scholar 

  15. Khaitan L, Van Sickle K, Gonzalez R, Lin E, Ramshaw B, Smith CD (2005) Laparoscopic revision of bariatric procedures: is it feasible? Am Surg 71(1):6–10

    PubMed  Google Scholar 

  16. Buchwald H, Campos CT (1997) Reoperations following surgery for morbid obesity. In: McQuarrie S (ed) Reoperative general surgery. Mosby-Year Book, Inc, St. Louis

    Google Scholar 

  17. McCormick JT, Papsavas PK, Caushaj PF et al (2003) Laparoscopic revision of failed open bariatric procedures. Surg Endosc 17:413–415

    Article  CAS  PubMed  Google Scholar 

  18. Hallowell PT, Stellato TA, Yao DA, Robinson A, Schuster MM, Graf KN (2009) Should bariatric revisional surgery be avoided secondary to increased morbidity and mortality? Am J Surg 197(3):391–396. https://doi.org/10.1016/j.amjsurg.2008.11.011

    Article  PubMed  Google Scholar 

  19. Hii MW, Lake AC, Kenfield C, Hopkins GH (2012) Laparoscopic conversion of failed gastric banding to Roux-en-Y gastric bypass. Short-term follow-up and technical considerations. Obes Surg 22(7):1022–1028. https://doi.org/10.1007/s11695-012-0594-3

    Article  CAS  PubMed  Google Scholar 

  20. Thompson CC (2004) Novel endoscopic approaches to common bariatric postoperative complications. Digestive Diseases Week. New Orleans, LA: Presented at the ASGE Video Forum

  21. Goyal V, Holover S, Garber S (2013) Gastric pouch reduction using StomaphyX in post Roux-en-Y gastric bypass patients does not result in sustained weight loss: a retrospective analysis. Surg Endosc 27(9):3417–3420

    Article  PubMed  Google Scholar 

  22. Jirapinyo P, Slattery J, Ryan MB, Abu Dayyeh BK, Lautz DB, Thompson CC (2013) Evaluation of an endoscopic suturing device for transoral outlet reduction in patients with weight regain following Roux-en-Y gastric bypass. Endoscopy 45(7):532–536

    Article  CAS  PubMed  Google Scholar 

  23. Kumar N, Thompson CC (2016) Transoral outlet reduction for weight regain after gastric bypass: long-term follow-up. Gastrointest Endosc 83(4):776–779. https://doi.org/10.1016/j.gie.2015.08.039

    Article  PubMed  Google Scholar 

  24. Mullady DK, Lautz DB, Thompson CC (2009) Treatment of weight regain after gastric bypass surgery when using a new endoscopic platform: initial experience and early outcomes. Gastrointest Endosc 70(3):440–444

    Article  PubMed  Google Scholar 

  25. Riva P, Perretta S, Swanstrom L (2017) Weight regain following RYGB can be effectively treated using a combination of endoscopic suturing and sclerotherapy. Surg Endosc 31(4):1891–1895. https://doi.org/10.1007/s00464-016-5189-y

    Article  PubMed  Google Scholar 

  26. Patel LY, Lapin B, Brown CS, Stringer T, Gitelis ME, Linn JG, Denham WE, Farwell E, Haggerty S, Ujiki MB (2016) Outcomes following 50 consecutive endoscopic gastrojejunal revisions for weight gain following Roux-en-Y gastric bypass: a comparison of endoscopic suturing techniques for stoma reduction. Surg Endosc 31(6):2667

    Article  PubMed  Google Scholar 

  27. Stier C, Chiappetta S (2016) Endoluminal revision (Overstitch (TM), Apollo Endosurgery) of the dilated gastroenterostomy in patients with late dumping syndrome after Proximal Roux-en-Y gastric bypass. Obes Surg 26(8):1978–1984. https://doi.org/10.1007/s11695-016-2266-1

    Article  PubMed  Google Scholar 

  28. Jirapinyo P, Dayyeh BK, Thompson CC (2016) Gastrojejunal anastomotic reduction for weight regain in roux-en-y gastric bypass patients: physiological, behavioral, and anatomical effects of endoscopic suturing and sclerotherapy. Surg Obes Relat Dis 12(10):1810–1816. https://doi.org/10.1016/j.soard.2016.09.036

    Article  PubMed  PubMed Central  Google Scholar 

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Funding

There was no external funding for this project.

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Correspondence to H. Mason Hedberg.

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Disclosures

Dr. Linn receives consulting fees from Medtronic, Dr. Ujiki receives consulting fees from Medtronic, GORE, and Apollo Endosurgery, Drs. Hedberg, Trenk and Ms. Kuchta and Carbray have nothing to disclose.

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Hedberg, H.M., Trenk, A., Kuchta, K. et al. Endoscopic gastrojejunostomy revision is more effective than medical management alone to address weight regain after RYGB. Surg Endosc 32, 1564–1571 (2018). https://doi.org/10.1007/s00464-018-6073-8

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  • DOI: https://doi.org/10.1007/s00464-018-6073-8

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