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Potent biomedical applications of isolated polysaccharides from marine microalgae Tetraselmis species

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Abstract

Microalgae Tetraselmis species were used to evaluate the biological characteristics of water-soluble polysaccharides (WSPs) as one of the significant bioactive substances (BAS) from these photosynthetic microalgae species. Compositional analysis of these BAS shows that they are mainly composed of WSPs along with negligible amount of proteins and lipids. WSPs were partially purified and characterized for their compositional, structural and biological properties such as antioxidant, tyrosinase inhibitory activity and antifungal activies. These WSPs showed the significant antioxidant, antifungal and tyrosinase inhibitory activities, respectively. The outcomes of this study demonstrated that WSPs can be the potent source of biological moieties for further investigations along with specific potent biological activities.

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Abbreviations

WSP:

Water-soluble polysaccharides

BAS:

Bioactive substances

T1:

KCTC 12236BP

T2:

KCTC 12432BP

DPPH:

1,1-Diphenyl-2-picrylhydrazyl

FRAP:

Ferric reducing antioxidant power

ABTS:

2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) di-ammonium salt TPTZ 2,4,6-tri(2-pyridyl)-s-triazine

TLC:

Thin-layer chromatography

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Acknowledgements

This research was supported by a grant from the Marine Biotechnology Program funded by the Ministry of Oceans and Fisheries.

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Authors and Affiliations

  1. Department of Life Sciences, College of Bionano, Gachon University, Seongnamdaero 1342, Seongnam-si, Gyeonggi-do, 461-701, Republic of Korea

    Shaheen Amna Kashif & Jae Kweon Park

  2. Department of Biomedical Engineering, College of Health Science, Gachon University, Incheon, 21936, Republic of Korea

    You Jin Hwang

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  1. Shaheen Amna Kashif
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Correspondence to Jae Kweon Park.

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Amna Kashif, S., Hwang, Y.J. & Park, J.K. Potent biomedical applications of isolated polysaccharides from marine microalgae Tetraselmis species. Bioprocess Biosyst Eng 41, 1611–1620 (2018). https://doi.org/10.1007/s00449-018-1987-z

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