Virchows Archiv

, Volume 473, Issue 1, pp 3–13 | Cite as

Vascular liver diseases on the clinical side: definitions and diagnosis, new concepts

  • Dominique-Charles Valla
  • Dominique Cazals-Hatem
Review and Perspectives
Part of the following topical collections:
  1. Vascular liver lesions: contemporary views on long-recognized entities


The components of the hepatic vascular system (hepatic arteries, portal and hepatic veins, sinusoids, and lymphatics) can be damaged by various types of injury. Each of the resulting conditions is rare, which has limited knowledge and awareness. In the last two decades, international collaborations have allowed to reach critical masses of data, which has driven significant progresses in understanding and management of vascular disorders of the liver. The present paper discusses definitions, denominations, and diagnosis of such vascular disorders with the exception of those affecting hepatic arteries. Evolving pathogenic or pathophysiologic views relevant to the clinical aspects are also overviewed.


Budd-Chiari syndrome Hepatic vein thrombosis Portal vein thrombosis Portal cavernoma Idiopathic portal hypertension Idiopathic noncirrhotic intrahepatic portal hypertension Obliterative portal venopathy Nodular regenerative hyperplasia Incomplete septal cirrhosis Hepatoportal sclerosis Sinusoidal obstruction syndrome Venoocclusive disease Nonobstructive sinusoidal dilatation Peliosis Congenital portosystemic shunt Abernethy malformation 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Dominique-Charles Valla
    • 1
    • 2
    • 3
  • Dominique Cazals-Hatem
    • 2
    • 3
    • 4
  1. 1.Service d’HépatologieHôpital BeaujonClichyFrance
  2. 2.DHU UNITY, APHP, Hôpital BeaujonClichy-la-GarenneFrance
  3. 3.CRI, UMR 1149, Université Paris-Diderot and InsermParisFrance
  4. 4.Service Central d’Anatomie et de Cytologie PathologiquesParisFrance

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