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Journal of Neurology

, Volume 265, Supplement 1, pp 3–8 | Cite as

Multicenter data banking in management of dizzy patients: first results from the DizzyNet registry project

  • Eva Grill
  • Gülden Akdal
  • Sandra Becker-Bense
  • Steffen Hübinger
  • Doreen Huppert
  • Erna Kentala
  • Ralf Strobl
  • Andreas Zwergal
  • Nese Celebisoy
Original Communication
First Online:
Received:
Revised:
Accepted:

Abstract

Purpose

Comprehensive phenotypical data across countries is needed to understand the determinants, prognosis and consequences of vestibular disease. The registry is a data repository for the members of the European DizzyNet. We report results from a pilot study using data from Turkey and Germany.

Methods

The pilot study included a convenience sample of patients aged 18 or above referred to Ege University Medical School Hospital, Dokuz Eylül University Hospital, Izmir, Turkey, and the German Center for German Center for Vertigo and Balance Disorders, University on Munich, Germany, with symptoms of vertigo or dizziness. Health-related quality of life was assessed with the EQ5-D and the Dizziness Handicap Inventory (DHI). To obtain comparable groups we matched data from the two countries for age, sex and diagnosis by propensity score.

Results

We included 80 adult patients, 40 from each country (60% female, mean age 54.1, SD 12.4). Matching was successful. Vestibular migraine (34%) was the most frequent diagnosis, followed by benign paroxysmal positional vertigo (29%) and Menière’s disease (12%). Clinical signs and symptoms were comparable in both countries. Patients from Turkey were more likely to report headaches (65 vs. 32%) and to show gait unsteadiness (51 vs. 5%). Patients from Germany reported significantly higher quality of life and lower values of the DHI score.

Conclusions

Sharing data facilitates research, enhances translation from basic science into clinical applications, and increases transparency. The DizzyNet registry is a first step to data sharing in vestibular research across Europe.

Keywords

Registries Vertigo Dizziness Quality of life Activities of daily living 
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Notes

Funding

This work was supported by funds from the German Federal Ministry of Education and Research under the grant code 01EO1401 as part of the European DizzyNet. The authors bear full responsibility for the content of this publication.

Compliance with ethical standards

Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical standards

All human and animal studies have been approved by the appropriate ethics committee and have, therefore, been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. We thank Amanda Phillips for copy-editing of the final manuscript.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute for Medical Information Processing, Biometrics and EpidemiologyLudwig-Maximilians-Universität MünchenMunichGermany
  2. 2.German Center for Vertigo and Balance Disorders, University HospitalLudwig-Maximilians-Universität MünchenMunichGermany
  3. 3.Munich Center of Health SciencesLudwig-Maximilians-Universität MünchenMunichGermany
  4. 4.Department of Neurology, Faculty of MedicineDokuz Eylül UniversityIzmirTurkey
  5. 5.Department of Neurology, University HospitalLudwig-Maximilians-Universität MünchenMunichGermany
  6. 6.Institute for Clinical Neurosciences, University HospitalLudwig-Maximilians-Universität MünchenMunichGermany
  7. 7.Department of OtorhinolaryngologyUniversity of HelsinkiHelsinkiFinland
  8. 8.Department of NeurologyEge UniversityIzmirTurkey

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