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Homozygosity for a NOTCH3 mutation in a 65-year-old CADASIL patient with mild symptoms

A family report

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Authors and Affiliations

  1. Dept. of Radiology, Leiden University Medical Center, C2S, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands

    M. K. Liem MD & J. van der Grond PhD

  2. Dept. of Clinical Genetics of the Center for Human and Clinical Genetics, Leiden University Medical Center, C2S, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands

    S. A. J. Lesnik Oberstein MD, PhD, M. J. Vollebregt MSc & A. T. J. M. Helderman-van den Enden MD

  3. Dept. of Neuropsychology of the Leiden, University Medical Center, Leiden University Medical Center, C2S, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands

    H. A. M. Middelkoop MD, PhD

  4. Dept. of Psychology, Leiden University, Rapenburg 70, 2300 RA, Leiden, The Netherlands

    H. A. M. Middelkoop MD, PhD

Authors
  1. M. K. Liem MD
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  2. S. A. J. Lesnik Oberstein MD, PhD
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  3. M. J. Vollebregt MSc
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  4. H. A. M. Middelkoop MD, PhD
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  5. J. van der Grond PhD
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  6. A. T. J. M. Helderman-van den Enden MD
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Correspondence to M. K. Liem MD.

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Liem, M.K., Lesnik Oberstein, S.A.J., Vollebregt, M.J. et al. Homozygosity for a NOTCH3 mutation in a 65-year-old CADASIL patient with mild symptoms. J Neurol 255, 1978–1980 (2008). https://doi.org/10.1007/s00415-009-0036-x

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  • DOI: https://doi.org/10.1007/s00415-009-0036-x

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