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Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler PlusTM multiplex in a population sample from Madhya Pradesh, India

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Abstract

We report here the first ever global study on genetic polymorphism using a Verifiler PlusTM autosomal STR multiplex system. The study evaluated genetic characteristics of 23 autosomal STRs in 200 unrelated residents of Guna district of Madhya Pradesh, India. Allele frequencies and forensic parameters are reported. Population comparison analysis was also performed using NJ tree and PCA plot. Penta E marker showed highest power of discrimination (0.938) among all 23 studied markers. The study also presents the first ever global forensic assessment in Indian population on D6S1043 marker (PD 0.937). The results demonstrated that all the 23 markers were highly polymorphic and the Verifiler PlusTM kit is suitable for forensic purposes in Indian population.

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References

  1. Dixit, S. et al. (2019) Forensic genetic analysis of population of Madhya Pradesh with PowerPlex Fusion 6CTM Multiplex System. International journal of legal medicine 1–3.

  2. Shrivastava P, Jain T, Trivedi VB (2015) Genetic polymorphism study at 15 autosomal locus in central Indian population. SpringerPlus 4:566–566

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Acknowledgments

The authors gratefully acknowledge the support of Director, State Forensic Science Laboratory, Sagar (MP), India, for providing laboratory facility as well as Thermo Fisher Scientific (India) for providing Verifiler PlusTM autosomal STR genotyping kit used in the study.

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Author notes

  1. Kamlesh Kaitholia, Shivani Dixit & Aditi Mishra

    Present address: DNA Fingerprinting Unit, State Forensic Science Laboratory, Department of Home (Police), Govt. of MP, Sagar, 470001, India

  2. Ankit Srivastava & Yash Baroniya

    Present address: Institute of Forensic Science and Criminology, Bundelkhand University, Jhansi, UP, 284128, India

Authors and Affiliations

  1. DNA Fingerprinting Unit, State Forensic Science Laboratory, Department of Home (Police), Govt. of MP, Sagar, 470001, India

    Pankaj Shrivastava, Hirak Ranjan Dash, Pushpesh Kushwaha, Manisha Rana, Akansha Dixit, Tanya Sarawagi, Alay Bhatt & Harsh Sharma

  2. DNA Division, State Forensic Science Laboratory, Rajasthan, Jaipur, 302016, India

    R. K. Kumawat

  3. Institute of Forensic Science and Criminology, Bundelkhand University, Jhansi, UP, 284128, India

    Pushpesh Kushwaha & Akansha Dixit

  4. Department of Forensic Science, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India

    Manisha Rana & Moumita Sinha

  5. Cytogenetics Laboratory, Dept. of Zoology, Banaras Hindu University, Varanasi, UP, 221005, India

    Gyaneshwer Chaubey

Authors
  1. Pankaj Shrivastava
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  2. Kamlesh Kaitholia
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  3. R. K. Kumawat
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  4. Shivani Dixit
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  5. Hirak Ranjan Dash
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  6. Ankit Srivastava
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  7. Yash Baroniya
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  8. Aditi Mishra
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  9. Pushpesh Kushwaha
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  10. Manisha Rana
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  11. Akansha Dixit
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  12. Tanya Sarawagi
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  13. Alay Bhatt
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  14. Harsh Sharma
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  15. Moumita Sinha
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  16. Gyaneshwer Chaubey
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Corresponding author

Correspondence to Pankaj Shrivastava.

Ethics declarations

The study was conducted in compliance with ethical standards. The study is approved by the ethical committee of Banaras Hindu University, Varanasi, India (Ref. No. I.Sc./ECM-XII/2018-19/06).

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The authors declare that they have no conflict of interest.

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Shrivastava, P., Kaitholia, K., Kumawat, R.K. et al. Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler PlusTM multiplex in a population sample from Madhya Pradesh, India. Int J Legal Med 134, 1327–1328 (2020). https://doi.org/10.1007/s00414-019-02172-4

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  • DOI: https://doi.org/10.1007/s00414-019-02172-4

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