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Forensic effectiveness and genetic distribution of 20 non-CODIS STRs and D3S1358 in Guangdong Han population

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Abstract

In this study, Guangdong Han population was analyzed with Goldeneye™ DNA ID 22NC Kit containing 20 non-CODIS STR loci and a CODIS STR locus. In 503 unrelated individuals, a total of 232 alleles and 813 genotypes were observed. The values of polymorphism information content (PIC), expected heterozygosity (He), and observed heterozygosity (Ho) ranged from 0.6678 to 0.8618, 0.7197 to 0.8757, and 0.6938 to 0.8767, respectively. No deviation from Hardy-Weinberg equilibrium was observed at all loci after the Bonferroni correction. The combined power of discrimination and the combined power of exclusion were 0.999999999999999999999999937051 and 0.999999998467033, respectively. Population comparison revealed that Guangdong Han population was relatively close to Huadong Han population. These results suggested that the 21 STR loci are highly polymorphic and Goldeneye™ DNA ID 22NC Kit is suitable for individual identification and paternity testing in Guangdong Han population.

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Funding

This work was financially supported by a grant from the Natural Science Foundation of Guangdong Province (Grant no. 2014A030310025).

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Author notes

  1. Hanhui Peng and Xiaopeng Li contributed equally to this work.

Authors and Affiliations

  1. School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, China

    Hanhui Peng, Xiaopeng Li, Ting Yao, Hongyan Huang, Cheng Xiao, Weibin Wu & Ling Chen

Authors
  1. Hanhui Peng
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  2. Xiaopeng Li
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  3. Ting Yao
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  4. Hongyan Huang
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  5. Cheng Xiao
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  6. Weibin Wu
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  7. Ling Chen
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Corresponding author

Correspondence to Ling Chen.

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The authors declare that they have no conflict of interest.

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• Goldeneye™ DNA ID 22NC Kit includes 20 non-CODIS STR loci and a CODIS STR locus.

• Goldeneye™ DNA ID 22NC Kit was firstly used to detect the genotypes and study the genetic polymorphism of the Guangdong Han population.

• Guangdong Han population has relatively close genetic relationship with the Huadong Han population.

• Goldeneye™ DNA ID 22NC Kit could be used for individual identification and paternity testing.

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Peng, H., Li, X., Yao, T. et al. Forensic effectiveness and genetic distribution of 20 non-CODIS STRs and D3S1358 in Guangdong Han population. Int J Legal Med 134, 1319–1321 (2020). https://doi.org/10.1007/s00414-019-02094-1

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  • DOI: https://doi.org/10.1007/s00414-019-02094-1

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