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Oxygen Desaturation in Daily Life and During a Laboratory-Based Protocol of Activities of Daily Living in COPD: Is There Relationship?

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Abstract

Purpose

To analyze the relationship between oxygen desaturation episodes during a laboratory-based ADL protocol and in real-life routine in patients with stable chronic obstructive pulmonary disease (COPD).

Methods

Twenty patients with stable COPD (12 men, 70 ± 7 years, FEV1% 54 ± 15 predicted) with no indication for long-term oxygen therapy (LTOT) were submitted to assessments including ADL performance by the Londrina ADL Protocol (LAP) and level of physical activity in daily life, both while submitted to simultaneous activity and pulse oximeter monitoring.

Results

Episodes of desaturation ≥ 4% (ED ≥ 4%) during the LAP were correlated both with ED ≥ 4% in daily life (r = 0.45) and number of episodes of SpO2 under 88% (ED < 88%) in daily life (r = 0.59). ED < 88% during the LAP was also correlated with ED < 88% in daily life (r = 0.51), explaining 43% of its variance.

Conclusion

In stable patients with COPD and no indication of LTOT, episodes of desaturation during a lab-based ADL protocol are moderately related to episodes of desaturation in daily (real) life, especially those episodes under 88%.

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Acknowledgement

The authors acknowledge the Conselho Nacional de Desenvolvimento Científico e Tecnológico—CNPq (Brazil), for the financial support.

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Authors and Affiliations

  1. Laboratory of Research in Respiratory Physiotherapy, Department of Physiotherapy, State University of Londrina, Av. Robert Koch, 60 – Vila Operária, Londrina, Parana, 86038-350, Brazil

    Thaís Sant’Anna, Leila Donária, Nidia A. Hernandes, Karina C. Furlanetto & Fabio Pitta

  2. Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Av. Robert Koch, 60 – Vila Operária, Londrina, Parana, 86038-350, Brazil

    Décio S. Barbosa

  3. Respiratory Division and Pulmonary Rehabilitation, University Hospitals, Katholieke Universiteit Leuven, Herestraat 49, 3000, Leuven, Belgium

    Rik Gosselink

Authors
  1. Thaís Sant’Anna
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  2. Leila Donária
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  3. Nidia A. Hernandes
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  4. Karina C. Furlanetto
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  5. Décio S. Barbosa
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  6. Fabio Pitta
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Corresponding author

Correspondence to Fabio Pitta.

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The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Sant’Anna, T., Donária, L., Hernandes, N.A. et al. Oxygen Desaturation in Daily Life and During a Laboratory-Based Protocol of Activities of Daily Living in COPD: Is There Relationship?. Lung 196, 19–26 (2018). https://doi.org/10.1007/s00408-017-0068-4

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  • DOI: https://doi.org/10.1007/s00408-017-0068-4

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