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Ossicular chain erosion in chronic otitis media patients with cholesteatoma or granulation tissue or without those: analysis of 915 cases

  • Otology
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Abstract

Purpose

The aim of this study was to evaluate the ossicular chain erosions (OCE) in chronic otitis media patients with cholesteatoma (COM-C) or without cholesteatoma (COM).

Materials and methods

The OCE and preoperative hearing levels of a total of 915 patients were evaluated retrospectively. Patients were divided into three groups. Of the 915 patients, 615 (67.2%) had COM, 234 (25.6%) had COM-C, and 66 (7.2%) had chronic otitis media with granulation tissue (COM-G).

Results

OCE was found in 291 (31.8%) of 915 patients. OCE was found in 192 (82%) of 234 patients with COM-C, 21 (31.8%) of 66 patients with COM-G, and 78 (12.7%) of 615 patients with COM.

Conclusion

The most commonly seen OCE was incus erosion, followed by stapes and malleus erosions. The results of this study show that there are more OCE in the COM-C group than in the COM-G and COM groups. To our knowledge, this study has the widest patient population in the literature focused on the OCE relation with COM, COM-C, and COM-G and its effect on the preoperative hearing level.

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References

  1. Xie S, Wang X, Ren J, Liu W (2017) The role of bone resorption in the etiopathogenesis of acquired middle ear cholesteatoma. Eur Arch Otorhinolaryngol 274(5):2071–2078

    Article  PubMed  Google Scholar 

  2. Choi SA, Kang HM, Byun JY, Park MS, Yeo SG (2014) Analysis of differences in facial nerve dehiscence and ossicular injury in chronic otitis media and cholesteatoma. Acta Otolaryngol 134(5):455–461

    Article  PubMed  Google Scholar 

  3. Kuczkowski J, Kobierska-Gulida G, Izycka-Swieszewska E, Potocka M, Mikaszewski B, Sierszeń W (2010) Molecular control of bone resorption in chronic otitis media with cholesteatoma. Otolaryngol Pol 64(4):219–224

    Article  PubMed  Google Scholar 

  4. Sabokbar A, Mahoney DJ, Hemingway F, Athanasou NA (2016) Non-canonical (RANKL-independent) pathways of osteoclast differentiation and their role in musculoskeletal diseases. Clin Rev Allergy Immunol 51(1):16–26

    Article  CAS  PubMed  Google Scholar 

  5. Chi Z, Wang Z, Liang Q, Zhu Y, du Q (2015) Induction of cytokine production in cholesteatoma keratinocytes by extracellular high-mobility group box chromosomal protein 1 combined with DNA released by apoptotic cholesteatoma keratinocytes. Mol Cell Biochem 400(1–2):189–200

    Article  CAS  PubMed  Google Scholar 

  6. Mohammadi G, Naderpour M, Mousaviagdas M (2012) Ossicular erosion in patients requiring surgery for cholesteatoma. Iran J Otorhinolaryngol 24(68):125–128

    PubMed  PubMed Central  Google Scholar 

  7. Varshney S, Nangia A, Bist SS, Singh RK, Gupta N, Bhagat S (2010) Ossicular chain status in chronic suppurative otitis media in adults. Indian J Otolaryngol Head Neck Surg 62(4):421–426

    Article  PubMed  Google Scholar 

  8. Albera R, Canale A, Piumetto E, Lacilla M, Dagna F (2012) Ossicular chain lesions in cholesteatoma. Acta Otorhinolaryngol Ital 32(5):309–313

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Wong J, Stoney P, Hawke M (1991) Ossicular erosion by cholesteatoma: investigation by scanning electron microscopy utilizing a new preparation technique. J Otolaryngol 20(3):216–221

    CAS  PubMed  Google Scholar 

  10. Martins O, Victor J, Selesnick S (2012) The relationship between individual ossicular status and conductive hearing loss in cholesteatoma. Otol Neurotol 33(3):387–392

    Article  PubMed  Google Scholar 

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Acknowledgements

We thank to Assoc. Prof. Oguz Kayiran to his effort for statistical analysis.

Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. This study was presented in 9th Cochlear Implant, otology-neurotology Congress (National) 7–10 December, 2017, Antalya, Turkey and 31th Politzer Society Meeting, 21–24 February, 2018, Las Palmas de Gran Canaria, Spain.

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Correspondence to M. Tayyar Kalcioglu.

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The authors declare that they have no competing interests.

Statement of human rights

The study has been approved by the Ethical Committee of the University Hospital and has been performed according to the ethical standards of the Helsinki Declaration. Because of it was a retrospective study, formal consent was not required. We declare that all authors have contributed to, read and approved the final manuscript for submission.

Ethical approval

This study was retrospectively data analysis study and it did not need to informed consent. This retrospective study was performed after approval of local ethic committee.

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Akarcay, M., Kalcioglu, M.T., Tuysuz, O. et al. Ossicular chain erosion in chronic otitis media patients with cholesteatoma or granulation tissue or without those: analysis of 915 cases. Eur Arch Otorhinolaryngol 276, 1301–1305 (2019). https://doi.org/10.1007/s00405-019-05339-2

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  • DOI: https://doi.org/10.1007/s00405-019-05339-2

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