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Impact of odontogenic chronic rhinosinusitis on general health-related quality of life

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Chronic rhinosinusitis (CRS) may arise due to odontogenic etiologies. However, it is unknown whether odontogenic CRS has a differential impact on patients’ quality of life (QOL) compared to standard, inflammatory (but non-odontogenic) CRS. The objective of this study was to determine whether there is a difference in the impact of sinonasal symptomatology on general health-related QOL in odontogenic CRS compared to non-odontogenic CRS. This was a retrospective review of 21 odontogenic CRS patients who visited our tertiary care center. The severity of sinonasal symptomatology and CRS-specific QOL detriment was measured using the 22-item Sinonasal Outcomes Test (SNOT-22) and general health-related QOL was measured using the health utility index from the 5-item EuroQol survey (EQ-5D HUV). Compared to non-odontogenic CRS, odontogenic CRS was not associated with a difference in SNOT-22 score [linear regression coefficient (β) = − 1.57, 95% CI − 12.47 to 9.32, p = 0.777] but was significantly associated with decreased EQ-5D HUV (β = − 0.10, 95% CI − 0.17 to − 0.03, p = 0.008). We also found that the magnitude of association (β) between SNOT-22 and EQ5D-HUV was greater for odontogenic CRS patients compared to non-odontogenic CRS patients (p = 0.045). Our findings suggest sinonasal symptoms may have a greater impact on general QOL in odontogenic CRS compared to non-odontogenic CRS. The reason for this remains unknown, but deserves further study.

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Acknowledgements

The authors gratefully acknowledge the contribution of the patients who participated in this study.

Funding

None.

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Authors and Affiliations

  1. Klinik für Mund- Kiefer- und Gesichtschirurgie, Universitätsmedizin Charité Berlin, Hindenburgdamm 30, 12203, Berlin, Germany

    Robert A. Gaudin & Max Heiland

  2. Department of Otolaryngology, Harvard Medical School, Boston, MA, USA

    Lloyd P. Hoehle, David S. Caradonna, Stacey T. Gray & Ahmad R. Sedaghat

  3. Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Lloyd P. Hoehle, Stacey T. Gray & Ahmad R. Sedaghat

  4. Klinik für Mund- Kiefer- und Gesichtschirurgie, Universitätsklinikum, Hamburg Eppendorf, Martinistraße 52, 20246, Hamburg, Germany

    Ralf Smeets

  5. Division Otolaryngology, Beth Israel Deaconness Medical Center, Boston, MA, USA

    David S. Caradonna & Ahmad R. Sedaghat

  6. Department of Otolaryngology and Communications Enhancement, Boston Children’s Hospital, Boston, MA, USA

    Ahmad R. Sedaghat

Authors
  1. Robert A. Gaudin
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  2. Lloyd P. Hoehle
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  3. Ralf Smeets
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  4. Max Heiland
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  5. David S. Caradonna
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  6. Stacey T. Gray
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  7. Ahmad R. Sedaghat
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Correspondence to Ahmad R. Sedaghat.

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The authors declare that there are no conflicts of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Gaudin, R.A., Hoehle, L.P., Smeets, R. et al. Impact of odontogenic chronic rhinosinusitis on general health-related quality of life. Eur Arch Otorhinolaryngol 275, 1477–1482 (2018). https://doi.org/10.1007/s00405-018-4977-5

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  • DOI: https://doi.org/10.1007/s00405-018-4977-5

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