Table 1 Demographic and ICSI cycle characteristics of patients

From: Correction to: Does timing in ICSI cycle affect oocyte quality and reproductive outcomes? A prospective study

Variable HCG-OPU ≤ 36 h (n = 264) HCG-OPU > 36 h (n = 349) P value
OPU-DN ≤ 2 h (n = 141) OPU -DN > 2 h (n = 123) OPU-DN ≤ 2 h (n = 180) OPU -DN > 2 h (n = 169)
DN-ICSI ≤ 2 h (n = 101) DN-ICSI > 2 h (n = 40) DN-ICSI ≤ 2 h (n = 75) DN-ICSI > 2 h (n = 48) DN-ICSI ≤ 2 h (n = 119) DN-ICSI > 2 h (n = 61) DN-ICSI ≤ 2 h (n = 104) DN-ICSI > 2 h (n = 65)
hCG-OPU interval (h), mean ± SD, range 35.7 ± 0.3, 35.0–36.0 35.8 ± 0.2, 35.0–36.0 35.7 ± 0.3, 35.0–36.0 35.7 ± 0.2, 35.1–36.0 36.8 ± 0.8, 36.1–41.7 36.7 ± 0.5, 36.1–38.2 36.9 ± 0.8, 36.1–40.3 36.7 ± 0.5, 36.1–38.7  
OPU-denudation (h), mean ± SD, range 1.5 ± 0.4, 0.5–2.0 1.4 ± 0.4, 0.6–2.0 3.2 ± 1.1, 2.1–5.8 2.9 ± 0.9, 2.1–6.0 1.3 ± 0.5, 0.2–2.0 1.4 ± 0.4, 0.2–2.0 3.4 ± 1.1, 2.1–6.0 3.2 ± 0.8, 2.1–5.5  
Denudation–ICSI (h), mean ± SD, range 1.1 ± 0.5, 0.1 -2.0 3.3 ± 1.0, 2.2–5.8 1.0 ± 0.5, 0.1–2.0 3.6 ± 1.2, 2.3–6.0 1.2 ± 0.6, 0.1–2.0 3.4 ± 1.1, 2.1–6.0 1.1 ± 0.5, 0.1–2.0 3.0 ± 0.8, 2.1–4.8  
Female age (Y) 33.6 ± 6.1 33.6 ± 6.5 31.2 ± 6.0a 32.7 ± 5.8 34.5 ± 6.5ab 34.4 ± 5.9 31.8 ± 5.8b 32.3 ± 5.5 0.003
BMI (kg/m2) 26.0 ± 4.1 25.7 ± 3.8 26.0 ± 3.3 26.2 ± 3.9 25.4 ± 4.1 24.5 ± 3.4 25.0 ± 3.9 26.7 ± 3.6 0.02
FSH (IU/mL) 6.5 ± 4.2 5.9 ± 2.9 5.8 ± 2.3 6.7 ± 4.8 6.1 ± 4.6 5.1 ± 2.5 6.3 ± 4.2 7.1 ± 7.9 0.9
AMH (ng/mL) 3.2 ± 2.9 3.8 ± 3.4 3.8 ± 3.9 3.8 ± 3.9 3.4 ± 3.4 4.7 ± 4.7 3.7 ± 4.1 4.5 ± 4.0 0.3
Primary infertility (n) 74 (73.3) 36 (90.0) 62 (82.7) 42 (87.5) 90 (75.6) 49 (80.3) 88 (84.6) 56 (86.1) 0.1
Secondary infertility (n) 27 (26.7) 4 (10.0) 13 (17.3) 6 (12.5) 29 (24.4) 12 (19.7) 16 (15.4) 9 (13.9)
Infertility duration (year) 5.3 ± 4.6 7.2 ± 6.7 4.8 ± 3.7 4.6 ± 3.6 5.6 ± 4.7 5.9 ± 4.7 5.3 ± 4.8 5.2 ± 4.3 0.6
No. of previous ICSI cycles          
 0 64 (63.4) 28 (70.0) 52 (69.3) 30 (62.5) 74 (62.1) 33 (54.1) 75 (72.1) 45 (69.2) 0.4
 1 27 (26.7) 8 (20.0) 14 (18.7) 13 (27.1) 27 (22.7) 13 (21.3) 17 (16.3) 10 (15.4)
 2 8 (7.9) 2 (5.0) 7 (9.3) 5 (10.4) 14 (11.8) 10 (16.4) 6 (5.8) 6 (9.2)
 ≥ 3 2 (2.0) 2 (5.0) 2 (2.7) 0 (0) 4 (3.4) 5 (8.2) 6 (5.8) 4 (6.2)  
Cause of infertility (n)          
 Male factor 47 (46.5) 24 (60.0) 39 (52.0) 21 (43.7) 41 (34.4) 27 (44.3) 49 (47.1) 29 (44.6) 0.1
 AMA 12 (11.9) 2 (5.0) 3 (4.0) 6 (12.5) 13 (10.9) 7 (11.5) 6 (5.8) 7 (10.8) 0.4
 DOR 21 (20.8) 7 (17.5) 6 (8.0) 6 (12.5) 26 (21.8) 6 (9.8) 8 (7.7) 4 (6.1) 0.004
 PCOS 25 (24.7) 11 (27.5) 16 (21.3) 16 (33.3) 20 (16.8) 14 (22.9) 22 (21.1) 18 (27.7) 0.4
Endometriosis 4 (4.0) 1 (2.5) 3 (4.0) 2 (4.2) 8 (6.7) 0 (0) 4 (3.8) 0 (0) 0.3
 RIF 7 (6.9) 4 (10.0) 6 (8.0) 2 (4.2) 7 (5.9) 10 (16.4) 6 (5.8) 9 (13.8) 0.1
 Uterine 7 (6.9) 1 (2.5) 5 (6.7) 2 (4.2) 12 (10.1) 4 (6.6) 6 (5.8) 6 (9.2) 0.7
 Others 14 (13.9) 5 (12.5) 10 (13.3) 5 (10.4) 17 (14.3) 9 (14.7) 18 (17.3) 10 (15.4) 0.9
Stimulation protocol (n)          
 Antagonist 97 (96.0) 37 (92.5) 71 (94.7) 45 (93.7) 110 (92.4) 56 (91.8) 97 (93.3) 63 (96.9) 0.8
 Agonist 4 (4.0) 3 (7.5) 4 (5.3) 3 (6.3) 9 (7.6) 5 (8.2) 7 (6.7) 2 (3.1)  
Total dose of gonadotrophins (IU) 2406.0 ± 1384.3 2815.6 ± 1435.2 2234.7 ± 956.7 1909.1 ± 994.1 2636.7 ± 1310.7 2581.4 ± 1548.7 2526.8 ± 1328.6 2076.9 ± 908.0 0.09
No. of embryos transferred 1.7 ± 0.5 1.7 ± 0.6 1.8 ± 0.5 1.7 ± 0.4 1.8 ± 0.6 1.9 ± 0.5 1.8 ± 0.5 1.7 ± 0.5 0.7