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Endoscopy-assisted inguinal lymphadenectomy in vulvar cancer

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

To explore the feasibility and efficiency of video endoscopic inguinal lymphadenectomy (VEIL) for vulvar cancer.

Methods

We evaluated 46 patients with vulvar cancer. Treatment included VEIL using the hypogastric subcutaneous approach (VEIL-H, 17 patients), VEIL with the limb subcutaneous surgical approach (VEIL-L, 8 patients), and open inguinal lymphadenectomy (OIL, 21 patients). All patients underwent radical vulvectomy; we evaluated operative time, the amount of bleeding, SF score, recurrence rate, etc.

Results

The durations of VEIL-H and VEIL-L were 170.79 ± 18.92 and 180.12 ± 17.88 min, respectively, which were longer than that of OIL (100.68 ± 11.37 min; P = 0.028). Bleeding volumes in the VEIL-H and VEIL-L groups were 15.23 ± 2.17 and 17.16 ± 2.35 ml, respectively; there were significantly lower than that of the OIL group (36.68 ± 3.48 ml; P = 0.021). The numbers of unilateral lymph nodes harvested were similar in all groups. The duration of hospitalization in VEIL group was shorter than that of the OIL group. There were less skin and lymphatic complications after VEIL than after OIL. Total SF-36 scores were significantly higher in the VEIL group than that in the OIL group (P = 0.032). There were no statistically significant differences in local recurrence, distant metastasis, and mortality among the three groups.

Conclusion

VEIL for vulvar cancer treatment is effective, with the advantages of short hospitalization stay, less bleeding, and reduced postoperative complications comparing the OIL.

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Funding

This study was funded by the Natural Science Foundation of Guangdong (Grant no. 2016A030313033).

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, The Nanshan Affiliated Hospital of Shenzhen University, Shenzhen, 518052, China

    Aiwen Le, Zhonghai Wang, Xiao yun Dai, Tian hui Xiao, Rong Zhuo & Ya hong Xu

  2. Department of Obstetrics and Gynaecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400011, China

    Jie Xiong & Rui Yuan

Authors
  1. Aiwen Le
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  2. Jie Xiong
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  3. Zhonghai Wang
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  4. Xiao yun Dai
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  5. Tian hui Xiao
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  6. Rong Zhuo
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  7. Ya hong Xu
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  8. Rui Yuan
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Contributions

AL: project development, data collection, and manuscript writing. JX: data collection. ZW: data collection; data analysis. XD: data collection. TX: data collection. RZ: data collection. YX: data collection. RY: project development and manuscript editing.

Corresponding author

Correspondence to Rui Yuan.

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Conflict of interest

We declare that we have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the First Affiliated Hospital of Chongqing Medical University research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Le, A., Xiong, J., Wang, Z. et al. Endoscopy-assisted inguinal lymphadenectomy in vulvar cancer. Arch Gynecol Obstet 297, 1277–1283 (2018). https://doi.org/10.1007/s00404-018-4732-6

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  • DOI: https://doi.org/10.1007/s00404-018-4732-6

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