Abstract
Purpose
Currently, endometrial polyps may be successfully treated in an outpatient setting with 5 Fr mechanical and bipolar instruments. Our aim is to evaluate the benefits of minimally invasive techniques in hysteroscopy, focusing on the use of a new dual wavelengths laser system in the treatment of endometrial polyps in an outpatient setting.
Methods
Between September 2012 and December 2014, all consecutive patients of reproductive and menopausal age with ultrasound diagnosis of endometrial polyp with maximum diameter ≤2.5 cm were eligible to participate in a prospective study. They underwent a hysteroscopic procedure with excision of the polyp using a new dual wavelengths laser system. All procedures were performed on an outpatient basis without anesthesia.
Results
Laser polypectomy was successfully performed in 219 out of 225 (97.3%). Success of surgery was not influenced by the initial location of polyp. No main complications were reported during or immediately after the procedure. 6 and 12 months follow-up with ultrasound scan did not show any persistence or recurrence of the pathology.
Conclusions
Our preliminary findings seem to support the safety and the effectiveness of the laser hysteroscopic endometrial polypectomy. However, further studies are mandatory to validate its use in daily hysteroscopic practice.
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References
Salim S, Won H, Nesbitt-Hawes E, Campbell N, Abbott J (2011) Diagnosis and management of endometrial polyps: a critical review of the literature. J Minim Invasive Gynecol 18:569–581
Lenci MA, Nascimento VA, Grandini AB, Fahmy WM, Depes Dde B, Baracat FF, Lopes RG (2014) Premalignant and malignant lesions in endometrial polyps in patients undergoing hysteroscopic polypectomy. Einstein (Sao Paulo) 12:16–21
Gkrozou F, Dimakopoulos G, Vrekoussis T, Lavasidis L, Koutlas A, Navrozoglou I, Stefos T, Paschopoulos M (2015) Hysteroscopy in women with abnormal uterine bleeding: a meta-analysis on four major endometrial pathologies. Arch Gynecol Obstet 291:1347–1354
Miranda SM, Gomes MT, Silva ID, Girão MJ (2010) Endometrial polyps: clinical and epidemiological aspects and analysis of polymorphisms. Rev Bras Ginecol Obstet 32:327–333
Serhat E, Cogendez E, Selcuk S, Asoglu MR, Arioglu PF, Eren S (2014) Is there a relationship between endometrial polyps and obesity, diabetes mellitus, hypertension? Arch Gynecol Obstet 290:937–941
Ferrazzi E, Zupi E, Leone FP, Savelli L, Omodei U, Moscarini M, Barbieri M, Cammareri G, Capobianco G, Cicinelli E, Coccia ME, Donarini G, Fiore S, Litta P, Sideri M, Solima E, Spazzini D, Testa AC, Vignali M (2009) How often are endometrial polyps malignant in asymptomatic post-menopausal women? Am J Obstet Gynecol 200:235.e1-6
de Azevedo JM, de Azevedo LM, Freitas F, Wender MC (2016) Endometrial polyps: when to resect? Arch Gynecol Obstet 293:639–643
Uglietti A, Mazzei C, Deminico N, Somigliana E, Vercellini P, Fedele L (2014) Endometrial polyps detected at ultrasound and rate of malignancy. Arch Gynecol Obstet 289:839–843
Bettocchi S, Nappi L, Ceci O, Selvaggi L (2003) What does ‘‘diagnostic hysteroscopy’’ mean today? The role of the new techniques. Curr Opin Obstet Gynecol 15:303–308
Bettocchi S, Nappi L, Ceci O, Selvaggi L (2004) Office hysteroscopy. Obstet Gynecol Clin North Am 31:641–654
Bettocchi S, Ceci O, Nappi L, Di Venere R, Masciopinto V, Pansini V, Pinto L, Santoro A, Cormio G (2004) Operative office hysteroscopy without anesthesia: analysis of 4863 cases performed with mechanical instruments. J Am Assoc Gynecol Laparosc 11:59–61
Bettocchi S, Ceci O, Di Venere R, Pansini MV, Pellegrino A, Marello F, Nappi L (2002) Advanced operative office hysteroscopy without anaesthesia: analysis of 501 cases treated with a 5 Fr. bipolar electrode. Hum Reprod 17:2435–2438
Nappi L, Sorrentino F, Angioni S, Pontis A, Greco P (2016) The use of laser in hysteroscopic surgery. Minerva Ginecol 68:722–726
Angioni S, Pontis A, Nappi L, Sedda F, Sorrentino F, Litta P, Haimovich S, Melis GB (2016) Endometrial ablation: first- vs. second-generation techniques. Minerva Ginecol 68:143–153
Angioni S, Pontis A, Sorrentino F, Nappi L (2015) Bilateral salpingo-oophorectomy and adhesiolysis with single port access laparoscopy and use of diode laser in a BRCA carrier Eur J. Gynecol Oncol 36:479–481
Angioni S, Mais V, Pontis A, Peiretti M, Nappi L (2014) First case of prophylactic salpingectomy with single port access laparoscopy and a new diode laser in a woman with BRCA mutation. Gynecol Oncol Case Rep 9:21–23
Nappi L, Angioni S, Sorrentino F, Cinnella G, Lombardi M, Greco P (2016) Anti-Mullerian hormone trend evaluation after laparoscopic surgery of monolateral endometrioma using a new dual wavelengths laser system (DWLS) for hemostasis. Gynecol Endocrinol 32:34–37
Coldren LA, Corzine SW, Mashanovitch ML (2012) Diode lasers and photonic integrated circuits, vol 218. Wiley, NY
Bettocchi S, Selvaggi L (1997) A vaginoscopic approach to reduce the pain of office hysteroscopy. J Am Assoc Gynecol Laparosc 4:255–258
Nappi L, Di Spiezio Sardo A, Spinelli M, Guida M, Mencaglia L, Greco P, Nappi C, Filippeschi M, Florio P (2013) A multicenter, double-blind, randomized, placebo-controlled study to assess whether antibiotic administration should be recommended during office operative hysteroscopy. Reprod Sci 20:755–761
Garuti G, Cellani F, Colonnelli M, Grossi F, Luerti M (2004) Outpatient hysteroscopic polypectomy in 237 patients: feasibility of a one-stop “see-and-treat” procedure. J Am Assoc Gynecol Laparosc 11:500–504
Haimovich S, Mancebo G, Alameda F, Agramunt S, Solé-Sedeno JM, Hernández JL, Carreras R (2013) Feasibility of a new two-step procedure for office hysteroscopy resection of submucous myomas: results of a pilot study. Eur J Obstet Gynecol Reprod Biol 168:191–194
Nappi L, Pontis A, Sorrentino F, Greco P, Angioni S (2016) Hysteroscopic metroplasty for the septate uterus with diode laser: a pilot study. Eur J Obstet Gynecol Reprod Biol 206:32–35
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Nappi, L., Sorrentino, F., Angioni, S. et al. Feasibility of hysteroscopic endometrial polypectomy using a new dual wavelengths laser system (DWLS): preliminary results of a pilot study. Arch Gynecol Obstet 295, 3–7 (2017). https://doi.org/10.1007/s00404-016-4232-5
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DOI: https://doi.org/10.1007/s00404-016-4232-5