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Fig. 1 | Archives of Dermatological Research

Fig. 1

From: Co-culture of human fibroblasts and Borrelia burgdorferi enhances collagen and growth factor mRNA

Fig. 1

a Interaction of B. afzelii and fibroblasts after co-culture for 24 h: B. afzelii bind to fibroblast membranes by tethers shown by an arrow. Borrelia seem to be invaginated in fibroblasts. Both the membranes of Borrelia and fibroblasts are intact. Ribosomes (RIB). b After 48 h intact, Borrelia is enclosed in a vesicle in the fibroblast’s cytoplasm, thus indicating that Borrelia passes through the cytoplasm. Multiple parallel and cross-sectioned filaments labelled as FIL—probably actin microfilaments—are seen in the vicinity with condensations at the fibroblast membrane surrounding the Borrelia forming attachment plaques for the filaments marked by triangles. Outer envelope of B. afzelii is marked by arrows. Endoplasmic reticulum is labelled by an asterisk

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