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ATP10B variants in Parkinson’s disease: a large cohort study in Chinese mainland population

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References

  1. Li C, Ou R, Chen Y, Gu X, Wei Q, Cao B et al (2020) ATP10B and the risk for early-onset Parkinson’s disease. Mov Disord 35:2359–2360. https://doi.org/10.1002/mds.28285

    Article  CAS  PubMed  Google Scholar 

  2. Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D et al (2020) Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol 139:1001–1024. https://doi.org/10.1007/s00401-020-02145-7

    Article  PubMed  PubMed Central  Google Scholar 

  3. Real R, Moore A, Blauwendraat C, Morris HR, Bandres-Ciga S, International Parkinson’s Disease Genomics C (2020) ATP10B and the risk for Parkinson’s disease. Acta Neuropathol 140:401–402. https://doi.org/10.1007/s00401-020-02172-4

    Article  PubMed  Google Scholar 

  4. Smolders S, Van Broeckhoven C (2020) Reply: ATP10B and the risk for Parkinson’s disease. Acta Neuropathol 140:403–404. https://doi.org/10.1007/s00401-020-02173-3

    Article  PubMed  Google Scholar 

  5. Smolders S, Van Broeckhoven C (2020) Reply: segregation of ATP10B variants in families with autosomal recessive Parkinsonism. Acta Neuropathol 140:787–789. https://doi.org/10.1007/s00401-020-02220-z

    Article  CAS  PubMed  Google Scholar 

  6. Tesson C, Lohmann E, Devos D, Bertrand H, Lesage S, Brice A (2020) Segregation of ATP10B variants in families with autosomal recessive Parkinsonism. Acta Neuropathol 140:783–785. https://doi.org/10.1007/s00401-020-02219-6

    Article  CAS  PubMed  Google Scholar 

  7. Zhao Y, Qin L, Pan H, Liu Z, Jiang L, He Y et al (2020) The role of genetics in Parkinson’s disease: a large cohort study in Chinese mainland population. Brain 143:2220–2234. https://doi.org/10.1093/brain/awaa167

    Article  PubMed  Google Scholar 

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Funding

This study was supported by the National Natural Science Foundation of China (Grant No. 82001359 and No. U20A20355), the National Key Research and Development Program of China (Grant No. 2016YFC1306000) and Hunan Innovative Province Construction Project (Grant No. 2019SK2335).

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Author notes

  1. Yuwen Zhao and Hongxu Pan have contributed equally to this work.

Authors and Affiliations

  1. Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan Province, China

    Yuwen Zhao, Hongxu Pan, Yige Wang, Qian Zeng, Runcheng He, Kun Xu, Xiaoxia Zhou, Xun Zhou, Zhou Zhou, Yanghong Li, Penghui Deng, Yinghui Xu, Qian Xu, Xinxiang Yan, Lu Shen, Hong Jiang, Jifeng Guo, Beisha Tang & Zhenhua Liu

  2. National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China

    Yuwen Zhao, Hongxu Pan, Bin Li, Guihu Zhao, Lu Shen, Hong Jiang, Jinchen Li, Jifeng Guo, Beisha Tang & Zhenhua Liu

  3. Centre for Medical Genetics and Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, 410008, Hunan, China

    Zhenghuan Fang, Jieqiong Tan, Jinchen Li, Jifeng Guo & Beisha Tang

  4. Department of Geriatrics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China

    Qiying Sun & Jinchen Li

  5. Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China

    Lifang Lei

  6. Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China

    Hainan Zhang & Chunyu Wang

  7. Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University, Changsha, 410008, Hunan, China

    Lu Shen, Hong Jiang, Jifeng Guo, Beisha Tang & Zhenhua Liu

Authors
  1. Yuwen Zhao
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  2. Hongxu Pan
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  3. Yige Wang
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  7. Kun Xu
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  8. Xiaoxia Zhou
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  9. Xun Zhou
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  10. Zhou Zhou
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  11. Yanghong Li
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  16. Bin Li
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  17. Guihu Zhao
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  18. Lifang Lei
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  19. Hainan Zhang
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  20. Chunyu Wang
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  21. Jieqiong Tan
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  22. Xinxiang Yan
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  23. Lu Shen
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  24. Hong Jiang
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  26. Jifeng Guo
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  27. Beisha Tang
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  28. Zhenhua Liu
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Corresponding author

Correspondence to Zhenhua Liu.

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Zhao, Y., Pan, H., Wang, Y. et al. ATP10B variants in Parkinson’s disease: a large cohort study in Chinese mainland population. Acta Neuropathol 141, 805–806 (2021). https://doi.org/10.1007/s00401-021-02280-9

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  • DOI: https://doi.org/10.1007/s00401-021-02280-9

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