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Infektionen

Infections

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Zusammenfassung

Die Einschätzung des Infektionsrisikos von Patienten mit rheumatologischen Erkrankungen basiert auf der sorgfältigen Erfassung der hierfür relevanten Faktoren wie der Grunderkrankung selbst, der Intensität der immunsuppressiven Therapie und der Schwere etwaiger Komorbiditäten. Aus infektiologischer Sicht sind hier besonders das wiederholte Auftreten schwerer Infektionen sowie Vorerkrankungen wie eine latente Tuberkulose oder eine chronische Hepatitis B oder C zu erwähnen. Dies kann eine prophylaktische antibiotische Therapie erforderlich machen, die ansonsten vermieden werden sollte, um nicht auf resistente Erreger zu selektionieren. Weiterhin sind Impfungen besonders geeignet das Risiko für häufige Infektionskrankheiten spezifisch zu minimieren.

Abstract

The individual risk assessment concerning infections in patients with rheumatic diseases is based on the detailed personalized documentation of relevant risk factors, such as the underlying disease itself, the intensity of immunosuppressive therapy and the severity of any comorbidities. From the perspective of infectiology, the history of repeated and severe infections as well as previous illnesses, such as (latent) tuberculosis and chronic hepatitis B or C need to be considered. In some instances prophylactic antibiotic therapy might be required, which should otherwise be avoided in order to prevent selection of resistant pathogens. Furthermore, vaccinations are particularly suitable to specifically minimize the risk for frequent infectious diseases.

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Authors and Affiliations

  1. Medizinische Universitätsklinik V: Hämatologie, Onkologie, Rheumatologie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland

    H.-M. Lorenz

  2. ACURA Rheumazentrum Baden-Baden, Baden-Baden, Deutschland

    H.-M. Lorenz

  3. Rheumatologische Facharztpraxis Schwerin, Beethovenstr. 3, 19053, Schwerin, Deutschland

    C. Kneitz

Authors
  1. H.-M. Lorenz
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Correspondence to C. Kneitz.

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H.-M. Lorenz und C. Kneitz geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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H.-M. Lorenz, Heidelberg

K. Krüger, München

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Lorenz, HM., Kneitz, C. Infektionen. Z Rheumatol 78, 236–242 (2019). https://doi.org/10.1007/s00393-018-0586-3

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  • DOI: https://doi.org/10.1007/s00393-018-0586-3

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