Präventionsstrategien gegen Demenz

  • Patrick Müller
  • Marlen Schmicker
  • Notger G. Müller
Beiträge zum Themenschwerpunkt

Zusammenfassung

Im Kontext des demografisch bedingten Anstiegs der Prävalenz von Demenzerkrankungen bei gleichzeitig fehlenden kausalen pharmakologischen Therapien gewinnen Präventionskonzepte zunehmend an Bedeutung. Durch gezielte Reduzierung von Risikofaktoren und Maßnahmen zur Induktion von Neuroplastizität kann erfolgreiches Altern unterstützt werden. Der Beitrag fasst die aktuellen Entwicklungen auf dem Gebiet der Demenzprävention durch Modifikation von Lebensstilfaktoren zusammen. Den Schwerpunkt bildet die Betrachtung des Einflusses von kognitiver und körperlicher Aktivität auf die Neuroprotektion. Ein vielversprechender Ansatz vereint die beiden Aktivitäten in einem Tanztraining. Auf die Notwendigkeit weiterer Studien, die den hohen Anforderungen einer randomisierten klinischen Studie gerecht werden, wird nachdrücklich hingewiesen.

Schlüsselwörter

Neuroplastizität Alzheimer-Krankheit Sport Tanzen Altern 

Preventive strategies for dementia

Abstract

In the context of the demographically induced increase in the prevalence of dementia and the simultaneous lack of causal pharmacological therapies, preventive approaches are gaining in importance. By reducing risk factors and with measures which induce neuroplasticity successful aging can be supported. This article summarizes the current developments in preventing dementia by modification of life style factors. The main focus lies on the impact of cognitive and physical activity on neuroprotection. A promising approach combines both activities within a dance training program. Further studies that meet the demanding criteria of a randomized clinical trial are urgently needed.

Keywords

Neuroplasticity Alzheimer disease Physical exercise Dancing Aging 

Notes

Einhaltung ethischer Richtlinien

Interessenkonflikt

P. Müller, M. Schmicker und N.G. Müller geben an, dass kein Interessenkonflikt besteht.

Alle im vorliegenden Manuskript beschriebenen Untersuchungen am Menschen wurden mit Zustimmung der zuständigen Ethikkommission, im Einklang mit nationalem Recht sowie gemäß der Deklaration von Helsinki von 1975 (in der aktuellen, überarbeiteten Fassung) durchgeführt. Von allen beteiligten Patienten liegt eine Einverständniserklärung vor.

The supplement containing this article is not sponsored by industry.

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Copyright information

© Springer Medizin Verlag GmbH 2017

Authors and Affiliations

  • Patrick Müller
    • 1
  • Marlen Schmicker
    • 1
  • Notger G. Müller
    • 1
    • 2
    • 3
  1. 1.AG NeuroprotektionDeutsches Zentrum für Neurodegenerative Erkrankungen (DZNE)MagdeburgDeutschland
  2. 2.Universitätsklinik für NeurologieOtto-von-Guericke-UniversitätMagdeburgDeutschland
  3. 3.Center for Behavioral Brain Sciences (CBBS)MagdeburgDeutschland

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