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Outcomes of laparoscopic surgery for pathological T4 colon cancer

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

The surgical indication of laparoscopic surgery for pT4 colon cancer remains to be established because only a few studies have investigated the short- and long-term outcomes of laparoscopic surgery for them to date. Therefore, we aimed to elucidate the validity of laparoscopic surgery for them.

Methods

We retrospectively analyzed 81 patients with pT4 colon cancer who underwent surgical resection with a curative intent at Kobe University Hospital from January 2007 to December 2015. The short- and long-term outcomes were compared between the propensity score–matched patients who underwent laparoscopic colectomy (LAP group, n = 25) and those who underwent open colectomy (OP group, n = 25).

Results

Intraoperative blood loss was significantly less in the LAP group than in the OP group (p = 0.029). Operative time, R0 resection rate, and morbidity did not significantly differ between the two groups. The 5-year overall survival (OS) and the 5-year recurrence-free survival (RFS) did not significantly differ between the propensity score–matched groups. Univariate and multivariate analyses of the entire cohort showed the surgical approach (LAP vs OP) selected was not a significant prognostic factor for OS or RFS.

Conclusions

The short and the long-term outcomes were similar between the LAP and OP groups. Laparoscopic surgery might be a safe and feasible option for pT4 colon cancer patients.

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Acknowledgments

The authors would like to thank Enago (www.enago.jp) for the English language review.

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Authors and Affiliations

  1. Division of Gastrointestinal Surgery, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan

    Tomoaki Aoki, Hiroshi Hasegawa, Kimihiro Yamashita, Yasuo Sumi, Ryo Ishida, Masashi Yamamoto, Shingo Kanaji, Taro Oshikiri, Tetsu Nakamura, Satoshi Suzuki & Yoshihiro Kakeji

  2. Division of Minimally Invasive Surgery, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

    Takeru Matsuda

  3. Division of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, Asahikawa, Japan

    Yasuo Sumi

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  1. Tomoaki Aoki
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  2. Takeru Matsuda
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Correspondence to Tomoaki Aoki.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Aoki, T., Matsuda, T., Hasegawa, H. et al. Outcomes of laparoscopic surgery for pathological T4 colon cancer. Int J Colorectal Dis 34, 1259–1265 (2019). https://doi.org/10.1007/s00384-019-03320-3

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  • DOI: https://doi.org/10.1007/s00384-019-03320-3

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