Fronto-orbital advancement in a patient with Marshall-Smith syndrome: a case report and review of the literature

Child's Nervous System volume 37, pages677–682(2021)Cite this article

Abstract

Objective

The present report aimed to document the clinical features of a case of Marshall-Smith syndrome (MSS), an extremely rare embryonic developmental disorder with associated craniosynostosis.

Patient and method

We presented herein a case of a 2-year-old female patient with MSS who underwent fronto-orbital advancement for multisuture craniosynostosis.

Results

The patient’s proptosis improved after surgery, and no further surgical intervention was required for corneal exposure. A second FOA followed by revision tarsorrhaphy further improved eye closure.

Conclusion

Surgical procedures to correct dysplastic features and limit neurological impairment are a worthwhile supportive treatment for improving the quality of life and general condition of patients with MSS.

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Author information

Affiliations

  1. Department of Neurosurgery, Vivantes Klinikum im Friedrichshain, Berlin, Germany

    Bettina Knie

  2. Division of Neurosurgery, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan

    Bettina Knie, Nobuhito Morota & Satoshi Ihara

  3. Division of Pediatric Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan

    Nobuhito Morota

  4. Department of Plastic and Reconstructive Surgery, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan

    Ikkei Tamada

Authors
  1. Bettina Knie
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  2. Nobuhito Morota
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  3. Satoshi Ihara
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  4. Ikkei Tamada
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Correspondence to Bettina Knie.

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Knie, B., Morota, N., Ihara, S. et al. Fronto-orbital advancement in a patient with Marshall-Smith syndrome: a case report and review of the literature. Childs Nerv Syst 37, 677–682 (2021). https://doi.org/10.1007/s00381-020-04741-0

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Keywords

  • Fronto-orbital advancement
  • Marshall-Smith syndrome
  • Craniofacial dysmorphism
  • Exophthalmos