Abstract
Purpose
Transcranial Doppler (TCD) has been used for more than 30 years in clinical practice. Although adult intensive care is relatively well covered, pediatric cases are still underrepresented. We intend to review a series of pediatric cases where TCD was determinant in clinical decisions and a literature review on this topic.
Methods
We describe cases with different pathologies where TCD had an important role in clinical management of the patients. We discuss TCD utility and potential role both in the emergency department and the intensive care unit.
Results
Five patients with different neurologic insults are presented. TCD was useful in the identification of intracranial hypertension in traumatic brain injury, hydrocephalus and central nervous system infection; identification of decreased cerebral perfusion pressure in hypovolemic shock and the diagnosis of impending cerebral circulatory arrest in a child with meningococcal septicemia. We discuss how TCD can be used in emergency and intensive care settings, reviewing relevant literature and our own experience.
Conclusions
Non-invasive testing using TCD can aid clinical decisions. More widespread use of this technique will allow for better care of children with neurologic insults.
Similar content being viewed by others
References
Aaslid R, Markwalder TM, Nornes H (1982) Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57(6):769–774
American Academy of Neurology (1990) T and TAS. Assessment: transcranial Doppler. Neurology 40:680–681
Goraj B, Rifkinson-Mann S, Leslie DR, Lansen TA, Kasoff SS, Tenner MS (1994) Correlation of intracranial pressure and transcranial Doppler resistive index after head trauma. AJNR Am J Neuroradiol 15:1333–1339
Moreno JA, Mesalles E, Gener J, Tomasa A, Ley A, Roca J et al (2000) Evaluating the outcome of severe head injury with transcranial Doppler ultrasonography. Neurosurg Focus 8(1):e8
Bellner J, Romner B, Reinstrup P, Kristiansson K-A, Ryding E, Brandt L (2004) Transcranial Doppler sonography pulsatility index (PI) reflects intracranial pressure (ICP). Surg Neurol 62(1):45–51 Available from: http://linkinghub.elsevier.com/retrieve/pii/S0090301904000448
Vieira F, Cardoso K, Abecasis F, Batista P, Boto L, Quintas S et al (2012) Doppler transcraniano na monitorização do traumatismo craniencefálico grave em pediatria. Acta Pediatr Port 43(6):239–245
de Riva N, Budohoski KP, Smielewski P, Kasprowicz M, Zweifel C, Steiner LA et al (2012) Transcranial Doppler pulsatility index: what it is and what it isn’t. Neurocrit Care 17(1):58–66. https://doi.org/10.1007/s12028-012-9672-6
Figaji AA, Zwane E, Fieggen AG, Siesjo P, Peter JC (2009) Transcranial Doppler pulsatility index is not a reliable indicator of intracranial pressure in children with severe traumatic brain injury. Surg Neurol. Elsevier Inc. 72(4):389–394. https://doi.org/10.1016/j.surneu.2009.02.012
Kochanek PM, Carney N, Adelson PD, Ashwal S, Bell MJ, Bratton S et al (2012) Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents—second edition. Pediatr Crit Care Med 1(1):S1–S82 Available from: http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00130478-201201001-00001
O’Brien NF, Maa T, Reuter-Rice K (2015) Noninvasive screening for intracranial hypertension in children with acute, severe traumatic brain injury. J Neurosurg Pediatr 16(4):420–425. https://doi.org/10.3171/2015.3.PEDS14521
Melo JRT, Di Rocco F, Blanot S, Cuttaree H, Sainte-Rose C, Oliveira-Filho J et al (2011) Transcranial Doppler can predict intracranial hypertension in children with severe traumatic brain injuries. Child’s Nerv Syst 27(6):979–984. https://doi.org/10.1007/s00381-010-1367-8
Reuter-Rice K (2017) Transcranial Doppler ultrasound use in pediatric traumatic brain injury. J Radiol Nurs 36(1):3–9 Available from: http://linkinghub.elsevier.com/retrieve/pii/S1546084316301900
LaRovere KL, O’Brien NF, Tasker RC (2016) Current opinion and use of transcranial Doppler ultrasonography in traumatic brain injury in the pediatric intensive care unit. J Neurotrauma 33(23):2105–2114. https://doi.org/10.1089/neu.2015.4344
Gosling R, King D (1974) Arterial assessment by Doppler-shift ultrasound. Proc R Soc Med 67:447–449
Czosnyka M, Matta BF, Smielewski P, Kirkpatrick PJ, Pickard JD (1998) Cerebral perfusion pressure in head-injured patients: a noninvasive assessment using transcranial Doppler ultrasonography. J Neurosurg 88(5):802–808. https://doi.org/10.3171/jns.1998.88.5.0802
Schmidt EA, Czosnyka M, Gooskens I, Piechnik SK, Matta BF, Whitfield PC et al (2001) Preliminary experience of the estimation of cerebral perfusion pressure using transcranial Doppler ultrasonography. J Neurol Neurosurg Psychiatry 70(2):198–204 Available from: http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=11160468&retmode=ref&cmd=prlinks%5Cnpapers2://publication/uuid/A6F19E20-AF9C-4C7C-836B-124522FD4785
Gura M, Silav G, Isik N, Elmaci I (2011) Noninvasive estimation of cerebral perfusion pressure with transcranial Doppler ultrasonography in traumatic brain injury. Turk Neurosurg 22(4):411–415. https://doi.org/10.5137/1019-5149.JTN.4201-11.1
Robba C, Cardim D, Sekhon M, Budohoski K, Czosnyka M (2018) Transcranial Doppler: a stethoscope for the brain-neurocritical care use. J Neurosci Res 96(4):720–730. https://doi.org/10.1002/jnr.24148
Bouzat P, Francony G, Declety P, Genty C, Kaddour A, Bessou P et al (2011) Transcranial doppler to screen on admission patients with mild to moderate traumatic brain injury. Neurosurgery 68(6):1603–1609
Trabold F, Meyer PG, Blanot S, Carli P, Orliaguet G (2004) The prognostic value of transcranial Doppler studies in children with moderate and severe head injury. Intensive Care Med 30(1):108–112 Available from: http://www.ncbi.nlm.nih.gov/pubmed/14600812
Levi C, Zareie H, Parsons M (2012) Transcranial Doppler in acute stroke management—a “real-time” bed-side guide to reperfusion and collateral flow. Perspect Med 1(1–12):185–193. https://doi.org/10.1016/j.permed.2012.02.044
Sampaio I, Abecasis F, Quintas S, Moreno T, Camilo C, Vieira M et al (2011) Successful intravenous thrombolysis in a 14-year-old boy with ischemic stroke. Pediatr Emerg Care 27(6):541–543
Kavi T, Esch M, Rinsky B, Rosengart A, Lahiri S, Lyden PD (2016) Transcranial Doppler changes in patients treated with extracorporeal membrane oxygenation. J Stroke Cerebrovasc Dis. Elsevier Inc. 25(12):2882–2885. https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.07.050
Marinoni M, Cianchi G, Trapani S, Migliaccio ML, Bonizzoli M, Gucci L et al (2018) Retrospective analysis of transcranial doppler patterns in veno-arterial extracorporeal membrane oxygenation patients. ASAIO J 64(2):175–182 Available from: http://insights.ovid.com/crossref?an=00002480-900000000-99032
Lindegaard K-F, Nornes H, Bakke SJ, Sorteberg W, Nakstad P (1988) Cerebral vasospasm after subarachnoid haemorrhage investigated by means of transcranial Doppler ultrasound. In: Proceedings of the 8th European Congress of Neurosurgery Barcelona, September 6–11, 1987. Springer Vienna, Vienna, pp 81–4. https://doi.org/10.1007/978-3-7091-8975-7_16
Saqqur M, Zygun D, Demchuk A (2007) Role of transcranial Doppler in neurocritical care. Crit Care Med 35(Suppl):S216–S223 Available from: http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00003246-200705001-00014
Lysakowski C, Walder B, Costanza MC, Tramèr MR (2001) Transcranial Doppler versus angiography in patients with vasospasm due to a ruptured cerebral aneurysm: a systematic review. Stroke 32(10):2292–2298
Burch CM, Wozniak MA, Sloan MA, Rothman MI, Rigamonti D, Permutt T et al (1996) Detection of intracranial internal carotid artery and middle cerebral artery vasospasm following subarachnoid hemorrhage. J Neuroimaging 6(1):8–15
Vora YY, Suarez-Almazor M, Steinke D, Martin M (1999) Role of transcranial Doppler monitoring in the diagnosis of cerebral vasospasm after subarachnoid hemorrhage. Neurosurgery 44(6):1237–1247
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
On behalf of all authors, the corresponding author states that there is no conflict of interest.
Rights and permissions
About this article
Cite this article
Abecasis, F., Oliveira, V., Robba, C. et al. Transcranial Doppler in pediatric emergency and intensive care unit: a case series and literature review. Childs Nerv Syst 34, 1465–1470 (2018). https://doi.org/10.1007/s00381-018-3877-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00381-018-3877-8