Abstract
Object
The aim of this paper is to review the current knowledge on the management of local infections in posterior cranial fossa (PCF) and spinal surgery; the center of our paper will be the diagnosis and management of infections of the wound, the subcutaneous tissue, and muscle strata.
Results and conclusions
Very few papers address the problem of local infections in posterior cranial fossa and spinal surgery. The largest amount of the literature data is indeed centered on how to deal with deep infections, CSF leak, and secondary meningitis or hardware infection. Concerning PCF surgery, a higher rate of local infections has been reported, compared with supratentorial surgery. To prevent such complications, prophylaxis remains the most important tool in dealing with local infections; a careful surgical planning and patient selection are also important. On the other hand, in dealing with local infection in spinal setting, there are several evidences that local vancomycin might help reducing them in adults as well as in children. The treatment protocol consists in antibiotic therapy and, whenever needed, wound revision to remove infectious material or to obtain a microbiological diagnosis. Prognosis has overall to be considered favorable both in the short term as well as in the long term.
Change history
08 March 2019
Unfortunately in the original publication, the affiliation provided for the author G. Tamburrini was incorrect. The correct affiliation for G. Tamburrini should read as follows: Fondazione Policlinico Universitario A. Gemelli IRCSS, Universit�� Cattolica del Sacro Cuore, Rome, Italy.
08 March 2019
Unfortunately in the original publication, the affiliation provided for the author G. Tamburrini was incorrect. The correct affiliation for G. Tamburrini should read as follows: Fondazione Policlinico Universitario A. Gemelli IRCSS, Universit�� Cattolica del Sacro Cuore, Rome, Italy.
References
Winn HR (2016) Youmans and Winn Neurological Surgery, vol 4. 7th edn. Elsevier, New York
Dubey A, Sung W-S, Shaya M, Patwardhan R, Willis B, Smith D, Nanda A (2009) Complications of posterior cranial fossa surgery—an institutional experience of 500 patients. Surg Neurol 72:369–375. https://doi.org/10.1016/j.surneu.2009.04.001
Hadanny A, Rozovski U, Nossek E, Shapira Y, Strauss I, Kanner AA, Sitt R, Ram Z, Shahar T (2016) Craniectomy versus craniotomy for posterior fossa metastases: complication profile. World Neurosurg 89:193–198. https://doi.org/10.1016/j.wneu.2016.01.076
Sciubba DM, Nelson C, Gok B, McGirt MJ, McLoughlin GS, Noggle JC, Wolinsky JP, Witham TF, Bydon A, Gokaslan ZL (2008) Evaluation of factors associated with postoperative infection following sacral tumor resection. J Neurosurg Spine 9:593–599. https://doi.org/10.3171/SPI.2008.9.0861
WHO (2016) Global Guidelines for the prevention of surgical site infection, Geneva
Hey HWD, Thiam DW, Koh ZSD, Thambiah JS, Kumar N, Lau LL, Liu KPG, Wong HK (2017) Is intraoperative local vancomycin powder the answer to surgical site infections in spine surgery? Spine 42:267–274. https://doi.org/10.1097/BRS.0000000000001710
Theologis AA, Demirkiran G, Callahan M, Pekmezci M, Ames C, Deviren V (2014) Local intrawound vancomycin powder decreases the risk of surgical site infections in complex adult deformity reconstruction: a cost analysis. Spine 39:1875–1880. https://doi.org/10.1097/BRS.0000000000000533
Sweet FA, Roh M, Sliva C (2011) Intrawound application of vancomycin for prophylaxis in instrumented thoracolumbar fusions: efficacy, drug levels, and patient outcomes. Spine 36:2084–2088. https://doi.org/10.1097/BRS.0b013e3181ff2cb1
Tubaki VR, Rajasekaran S, Shetty AP (2013) Effects of using intravenous antibiotic only versus local intrawound vancomycin antibiotic powder application in addition to intravenous antibiotics on postoperative infection in spine surgery in 907 patients. Spine 38:2149–2155. https://doi.org/10.1097/BRS.0000000000000015
Armaghani SJ, Menge TJ, Lovejoy SA, Mencio GA, Martus JE (2014) Safety of topical vancomycin for pediatric spinal deformity: nontoxic serum levels with supratherapeutic drain levels. Spine 39:1683–1687. https://doi.org/10.1097/BRS.0000000000000465
Gans I, Dormans JP, Spiegel DA, Flynn JM, Sankar WN, Campbell RM, Baldwin KD (2013) Adjunctive vancomycin powder in pediatric spine surgery is safe. Spine 38:1703–1707. https://doi.org/10.1097/BRS.0b013e31829e05d3
Wang J, Zhang H, Wang S (2015) Application of vacuum sealing drainage in the treatment of internal fixation instrument exposure after early postoperative infection. Minerva Chir 70:17–22
Masumoto K, Nagata K, Oka Y, Kai H, Yamaguchi S, Wada M, Kusuda T, Hara T, Hirose SI, Iwasaki A, Taguchi T (2011) Successful treatment of an infected wound in infants by a combination of negative pressure wound therapy and arginine supplementation. Nutrition 27:1141–1145. https://doi.org/10.1016/j.nut.2011.01.006
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Bianchi, F., Tamburrini, G. Posterior cranial fossa and spinal local infections. Childs Nerv Syst 34, 1889–1892 (2018). https://doi.org/10.1007/s00381-018-3796-8
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DOI: https://doi.org/10.1007/s00381-018-3796-8