Child's Nervous System

, Volume 34, Issue 7, pp 1407–1410 | Cite as

Persistent craniopharyngeal canal, bilateral microphthalmia with colobomatous cysts, ectopic adenohypophysis with Rathke cleft cyst, and ectopic neurohypophysis: case report and review of the literature

  • Nazlı Gülsüm Akyel
  • Ayşe Gül Alımlı
  • Tülin Hakan Demirkan
  • Mesut Sivri
Case Report



Persistent craniopharyngeal canal (PCC) is a rare anomaly of the base of the skull. PCC is defined as a well-corticated osseous canal, extending from the roof of the nasopharynx to the base of the sella over the course of the sphenoid corpus. We reported a PCC case with unique associations. The magnetic resonance imaging findings are discussed.

Case presentation

We report a case of a 2-year-old boy with persistent craniopharyngeal canal, bilateral microphtalmia with large colobomatous cyst, and ectopic adenohypophysis with Rathke cleft cyst. He also has ectopic neurohypophysis and optic atrophy.


The presence of orbital and optic tract malformations, craniofacial and intracranial anomalies, and tumors can accompany craniopharyngeal canals (CCs). MRI is helpful in the evaluation of PCC and associated anomalies in these patients.


Craniopharyngeal canal Colobomatous cyst Ectopic neurohypophysis Rathke cleft Cyst Microphtalmos with cyst 


Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Nazlı Gülsüm Akyel
    • 1
  • Ayşe Gül Alımlı
    • 1
  • Tülin Hakan Demirkan
    • 1
  • Mesut Sivri
    • 1
  1. 1.Department of Radiology, Ankara Child Health and Diseases Hematology Oncology Training and Research HospitalUniversity of Health SciencesAnkaraTurkey

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