Abstract
Case report
The authors report the case of an immature teratoma of the left parieto-occipital region in a 13-year-old girl. The patient had a computed tomographic (CT) scan of the brain aged 10 months old, following a minor head injury. This demonstrated an abnormality in the same region, which had been reported as ‘a cortical malformation’.
Diagnosis
We propose that the lesion on the original imaging is a mature teratoma or other silent dystopic germ cell element that subsequently transformed into the immature teratoma.
Discussion
The potential triggers for such a transformation and the management of patients with similar incidental radiological findings are discussed.
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References
Bjornsson J, Scheithauer BW, Okazaki H, Leech RW (1985) Intracranial germ cell tumors: pathological and immunohistochemical aspects of 70 cases. J Neuropathol Exp Neurol 44:32–46
DiSaia PJ, Saltz A, Kagan AR, Morrow CP (1977) Chemotherapeutic retroconversion of immature teratoma of the ovary. Obstet Gynecol 49:346–350
Hong WK, Wittes RE, Hajdu ST, Cvitkovic E, Whitmore WF, Golbey RB (1977) The evolution of mature teratoma from malignant testicular tumors. Cancer 40:2987–2992
Ingraham FD, Bailey OT (1946) Cystic teratomas and teratoid tumours of the central nervous system in infancy and childhood. J Neurosurg 3:511–514
Jennings MT, Gelman R, Hochberg F (1985) Intracranial germ cell tumors: natural history and pathogenesis. J Neurosurg 63:155–167
Kleihues P, Burger PC, Scheithauer BW (eds) (1993) Histological typing of tumours of the central nervous system, 2nd edn. Springer, Berlin Heidelberg New York, p 46
Lijuen L, Minyi T, Tonghua L (1980) Retroconversion of ovarian teratoma malignancy. Chin Med J 93:24–30
Parisi JE, Mena H (1993) Nonglial tumors. In: Nelson JS, Parisi JE, Schochet SS (eds) Principles and practice of neuropathology. Mosby, St Louis
Rueda-Pedraza ME, Heitetz SA, Sesterhenn IA, Clark GB (1987) Primary intracranial germ cell tumours in the first two decades of life: a clinical, light-microscopic and immunohistochemical analysis of 54 cases. Perspect Pediatr Pathol 10:160–207
Shaffrey ME, Lanzino G, Lopes BS, Hessler RB, Kassell NF, Vandenberg SR (1996) Maturation of intracranial immature teratomas. J Neurosurg 85:672–676
Zulch KJ (1986) Brain tumours. Their biology and pathology, 3rd edn. Springer, Berlin Heidelberg New York, pp 414–425
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Hanna, S.J., Green, A.L., Ansorge, O. et al. Immature teratoma arising from a benign cortical abnormality. Childs Nerv Syst 22, 164–167 (2006). https://doi.org/10.1007/s00381-004-1093-1
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DOI: https://doi.org/10.1007/s00381-004-1093-1