Effects of intracerebroventricular arginine vasotocin on a female amphibian proceptive behavior
- 369 Downloads
Mate choice decisions of animals show significant variability—both among and within individuals. Clearly, such variability can profoundly impact individual fitness, as well as subtly alter sexual selection processes, but we know little about the neural mechanisms underlying such variability. We examined the influence of the neuropeptide arginine vasotocin (AVT) on the strength of attraction of female gray treefrogs (Hyla versicolor) showing positive phonotaxis to the call of a conspecific male. Female treefrogs received intracerebroventricular injections with either saline, AVT (five doses), or the AVT receptor antagonist Manning compound (two doses). By 30 min after injection, AVT significantly increased the speed with which females approached the speaker, at doses of 1, 10 and 50 ng per frog. At the highest dose, the average speed was doubled. The AVT antagonist significantly inhibited phonotaxis at both doses (50 and 100 ng). The effects of AVT on treefrog phonotaxis were shorter lived (disappearing within 60–90 min), compared to Manning compound (effects persisted at least 90 min). These findings support the hypothesis that endogenous AVT is critical to the display of female phonotaxis behavior. AVT may thus contribute to variability in female mate choices by modulating proceptive behaviors.
KeywordsVasotocin Amphibian Phonotaxis Hyla versicolor Mate choice
The author gratefully acknowledges the support of the National Science Foundation (IOS # 0725187, 1257777) and the helpful comments of two anonymous reviewers. All applicable national and institutional guidelines for the care and use of animals were followed.
Compliance with ethical standards
Conflict of interest
The author declares no conflicts of interest.
- Dewan AK, Ramey ML, Tricas TC (2011) Arginine vasotocin neuronal phenotypes, telencephalic fiber varicosities, and social behavior in butterflyfishes (Chaetodontidae): potential similarities to birds and mammals. Horm Behav 59:56–66. https://doi.org/10.1016/j.yhbeh.2010.10.002 CrossRefPubMedGoogle Scholar
- Gerhardt HC, Huber F (2002) Acoustic communication in insects and anurans: common problems and diverse solutions. University of Chicago Press, ChicagoGoogle Scholar
- Gobbetti A, Zerani M (1992) A possible involvement of prostaglandin F2-alpha (PGF2-alpha) in Rana esculenta ovulation—effects of mammalian gonadotropin releasing hormone on in vitro PGF2-alpha and 17-beta-estradiol production from ovary and oviduct. Gen Comp Endocrinol 87:163–170. https://doi.org/10.1016/0016-6480(92)90018-f CrossRefPubMedGoogle Scholar
- Goodson JL (2008) Nonapeptides and the evolutionary patterning of sociality. In: Neumann ID, Landgraf R (eds) Advances in vasopressin and oxytocin: from genes to behaviour to disease, vol 170. Progress in Brain Research, pp 3–15. https://doi.org/10.1016/s0079-6123(08)00401-9
- Guillette LJ, Norris DO, Norman MF (1985) Response of amphibian (Ambystoma tigrinum) oviduct to arginine vasotocin and acetylcholine in vitro—influence of steroid hormone pretreatment in vivo. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 80:151–154. https://doi.org/10.1016/0742-8413(85)90147-1 CrossRefGoogle Scholar
- Hall IC, Woolley SMN, Kwong-Brown U, Kelley DB (2016) Sex differences and endocrine regulation of auditory-evoked, neural responses in African clawed frogs (Xenopus). J Comp Physiol A Neuroethol Sens Neural Behav Physiol 202:17–34. https://doi.org/10.1007/s00359-015-1049-9 CrossRefPubMedGoogle Scholar
- Jones RE, Guillette LJ (1982) Hormonal control of oviposition and parturition in lizards. Herpetologica 38:80–93Google Scholar
- Miranda RA, Searcy BT, Propper CR (2015) Arginine vasotocin induces calling behavior with a female social stimulus and interacts with gonadotropins to affect sexual behaviors in male Xenopus tropicalis. Physiol Behav 151:72–80. https://doi.org/10.1016/j.physbeh.2015.06.031 CrossRefPubMedGoogle Scholar
- Vu M, Weiler B, Trudeau VL (2017) Time- and dose-related effects of a gonadotropin-releasing hormone agonist and dopamine antagonist on reproduction in the Northern leopard frog (Lithobates pipiens). Gen Comp Endocrinol 254:86–96. https://doi.org/10.1016/j.ygcen.2017.09.023 CrossRefPubMedGoogle Scholar