Preoperative localisation of pulmonary ground-glass opacity using medical adhesive before thoracoscopic resection
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To evaluate the safety and efficiency of computed tomography (CT)-guided medical adhesive, α-cyanoacrylate, for preoperative localisation of pulmonary ground-glass opacity (GGO) used for guiding the video-assisted thoracoscopic surgical (VATS) excision
The procedure was performed on 188 consecutive patients with solitary GGO (pure GGO = 90 cases; mixed GGO = 98 cases) prior to the thoracoscopic procedure. The complications and efficacy of this method were analysed. The resected GGO was analysed pathologically.
The mean duration of the procedure was 16.3 ± 5.2 min. The preoperative localisation was 100% successful. All GGOs were successfully resected by VATS. Asymptomatic pneumothorax was developed in 16/188 patients (8.5%) and mild pulmonary haemorrhage occurred in 15 cases (7.9%) post-localisation. None of the patients required any further treatment for the complications.
Preoperative localisation using CT-guided medical adhesive, α-cyanoacrylate, is a safe and short-duration procedure, with high accuracy and success rates with respect to VATS resection of GGO.
• Preoperative localisation is crucial for successful resection of GGO by VATS.
• Preoperative adhesive localisation provides an up to 100% successful localisation rate with few complications.
• Preoperative adhesive localisation enabled VATS resection in 100% of the GGO.
• Preoperative adhesive localisation is safe and effective for VATS resection of GGO.
KeywordsSolitary pulmonary nodule Lung neoplasms Tomography, x-ray computed Tissue adhesives Thoracic surgery, video-assisted
Video-assisted thoracoscopic surgery
This study has received funding from the Medical Scientific Research Foundation of Guangdong Province, China (A2016410), and National Natural Science Foundation of China (81601457)
Compliance with ethical standards
The scientific guarantor of this publication is Qingsi Zeng.
Conflict of interest
The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
Statistics and biometry
No complex statistical methods were necessary for this paper.
Written informed consent was waived by the Institutional Review Board.
Institutional Review Board approval was obtained.
• performed at one institution