Abstract
Objective
Solitary fibrous tumours (SFTs) occurring in the spine are rare. Herein, we review the clinical and imaging data of spinal SFT.
Methods
We retrospectively analysed eight cases of pathologically confirmed spinal SFT imaging and clinical data, pathological manifestations, surgical methods, and follow-up results.
Results
Five SFTs cases occurred in the cervical spine, two in the thoracic spine, and one in the lumbosacral spine. Five cases showed a dumbbell-shaped or lobulated soft tissue mass that grew across the intervertebral foramen, two cases showed an expansive intraosseous mass formation in the vertebral body and/or posterior element, and one case showed a long-spindle shaped intraspinal canal mass growing along the spinal canal. Seven caused local invasion and destruction of the vertebral body and posterior element. Benign SFTs displayed a good prognosis, whereas malignant SFTs were prone to recurrence and metastasis (3/4).
Conclusion
Spinal SFTs are difficult to characterise with imaging and required pathological and immunohistochemical investigation. Prolonged follow-up is recommended once a diagnosis of spinal SFTs has been established because of the unclear biology.
Key Points
• Spinal solitary fibrous tumours are extremely rare.
• SFTs should be showed the differential of masses developing though the foramen.
• Combing imaging with pathology and immunochemistry assesses the diagnosis and establish nature.
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Abbreviations
- CT:
-
Computed tomography
- CTV:
-
Clinical tumour volume
- GTR:
-
Gross total resection
- GTV:
-
Gross tumour volume
- HPFs:
-
High-power fields
- MR:
-
Magnetic resonance
- PGTV:
-
Planning gross tumour volume
- PTV:
-
Planning target volume
- SFT:
-
Solitary fibrous tumour
- T1WI:
-
T1-weighted imaging
- T2WI:
-
T2-weighted imaging
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Funding
This study has received funding by National Natural Science Foundation of China (81701648) and Beijing Municipal Natural Science Foundation (7164309) and National Natural Science Foundation of China(81471634).
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The scientific guarantor of this paper is professor Min-Ying Su. 164 Irvine Hall, Center for Functional Onco-Imaging, University of California, Irvine,CA 92697-5020. E-mail: msu@uci.edu
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The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
Statistics and biometry
No complex statistical methods were necessary for this paper.
Informed consent
Written informed consent was obtained from all subjects (patients) in this study.
Ethical approval
Institutional Review Board approval was obtained.
Methodology
• Retrospective
• Diagnostic or prognostic study
• Performed at one institution
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Lang, N., Zhang, E., Xing, X. et al. Solitary fibrous tumour of the spine: imaging features of a commonly misdiagnosed entity. Eur Radiol 28, 3986–3995 (2018). https://doi.org/10.1007/s00330-018-5349-7
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DOI: https://doi.org/10.1007/s00330-018-5349-7