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CAIPIRINHA-Dixon-TWIST (CDT)-VIBE MR imaging of the liver at 3.0T with gadoxetate disodium: a solution for transient arterial-phase respiratory motion-related artifacts?

  • Hepatobiliary-Pancreas
  • Published:
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Abstract

Purpose

To determine whether CAIPIRINHA-Dixon-TWIST (CDT) volume-interpolated breath-hold examination (VIBE) improves image quality by reducing gadoxetate-disodium-associated transient arterial-phase motion artefacts in magnetic resonance imaging (MRI) of the liver.

Materials and methods

MRI studies of the liver from 270 patients who had received gadoxetate disodium were retrospectively evaluated in regard to arterial timing accuracy and arterial phase motion artefact severity (VIBE: 90/270, CAIPIRINHA-VIBE: 90/270 and CDT-VIBE: 90/270 cases). Three independent and blinded readers assessed arterial phase timing and motion artefact severity (5-point scale). Interrater agreement was calculated by weighted kappa. Continuous variables were compared via a two-sided ANOVA, categorical variables via a χ2 test. An ordinal regression analysis was performed to identify other predictors of motion artefacts.

Results

CDT-VIBE improved correct late arterial timing rates and reduced motion-related image deterioration rates. Successful late arterial liver visualisation was achieved in 56.7% (VIBE) compared with 66.7% (CAIPIRINHA-VIBE) and 84.4% (CDT-VIBE) (P < 0.0001). Good/excellent image quality was achieved in 56.7% vs. 66.7% and 73.3%, respectively (P = 0.03). Male sex negatively influenced image quality (P = 0.03).

Conclusion

CDT-VIBE increases the diagnostic utility of gadoxetate disodium-based liver MRI by reducing respiratory motion artefacts and optimising late arterial visualisation compared with VIBE and CAIPIRINHA-VIBE.

Key Points

• CAIPIRINHA-Dixon-TWIST-VIBE-MRI (CDT) mitigates effects of acute transient dyspnoea caused by gadoxetate disodium.

• CDT improves late arterial imaging compared with VIBE and CAIPIRINHA-VIBE.

• The rate of ideal late arterial images is higher with CDT-VIBE vs. VIBE or CAIPI-VIBE.

• The impact of respiratory motion artefacts on arterial phase images can be reduced.

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Abbreviations

CAIPIRINHA:

Controlled Aliasing In Parallel Imaging Results In Higher Acceleration Factor

TWIST:

Time-resolved Angiography With Interleaved Stochastic Trajectories

CDT:

CAIPIRINHA-Dixon TWIST

VIBE:

Volume-interpolated Breath-hold Examination

HASTE:

Half Fourier Acquisition Single-shot Turbo Spin Echo

MRI:

Magnetic Resonance Imaging

CT:

Computed Tomography

TSM:

Transient Severe Motion

T2w:

T2 Weighted

HCC:

Hepatocellular Carcinoma

PACS:

Picture Archiving And Communication System

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Funding

The authors state that this work has not received any funding.

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Authors and Affiliations

  1. Department of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria

    Leonhard Gruber, Vera Rainer, Michaela Plaikner, Christian Kremser, Werner Jaschke & Benjamin Henninger

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  1. Leonhard Gruber
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  2. Vera Rainer
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  3. Michaela Plaikner
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  4. Christian Kremser
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  5. Werner Jaschke
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  6. Benjamin Henninger
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Correspondence to Benjamin Henninger.

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The scientific guarantor of this publication is Benjamin Henninger.

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The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Statistics and biometry

Two of the authors have significant statistical expertise.

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Written informed consent was not required for this study because of its retrospective nature

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Institutional Review Board approval was obtained.

Methodology

• retrospective

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• performed at one institution

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Gruber, L., Rainer, V., Plaikner, M. et al. CAIPIRINHA-Dixon-TWIST (CDT)-VIBE MR imaging of the liver at 3.0T with gadoxetate disodium: a solution for transient arterial-phase respiratory motion-related artifacts?. Eur Radiol 28, 2013–2021 (2018). https://doi.org/10.1007/s00330-017-5210-4

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  • DOI: https://doi.org/10.1007/s00330-017-5210-4

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