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Quantitative cartilage volume measurement using MRI: comparison of different evaluation techniques

  • Musculoskeletal
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Abstract

This study was aimed to investigate the accuracy and time saving of MRI Argus application in the assessment of cartilage volume in osteoarthritic knees. Twelve knees of patients suffering from osteoarthritis were scanned with a 1.5 T MRI using a 3D gradient echo sequence with selective water excitation. Cartilage volume of the tibial and patellar compartment was determined with a validated multiprocessing computer system (Octane Duo, Silicon Graphics, Mountain View, Calif., USA). The calculated cartilage volumes were compared to the results acquired by the Argus (Siemens Inc., Erlangen, Germany) application software using the MRI data sets. Compared to the multiprocessing computer system a time saving of at least 30 min for cartilage volume determination was achieved. The mean differences of Argus versus the multiprocessing computer system were 4.26±0.84 and 7.80±0.87% for the medial and lateral tibial plateau and 5.94±0.59% for the patella (no statistical significant difference; P>0.05). The applied Argus software can be used for fast and accurate determination of cartilage volume in the knee joint.

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References

  1. Felson DT, Naimark A, Anderson J, Kazis L, Castelli W, Meenan RF (1987) The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthr Rheum 30:914–918

    Google Scholar 

  2. Preidler KW, Resnick D (1996) Imaging of osteoarthritis. Radiol Clin N Am 34:259–271

    Google Scholar 

  3. Ayral X, Gueguen A, Ike RW, Bonvarlet JP, Frizziero L, Kalunian K, Moreland LW, Myers S, O’Rourke KS, Roos H, Altman R, Dougados M (1998) Inter-observer reliability of the arthroscopic quantification of chondropathy of the knee. Osteoarthr Cartil 6:160–166

    Google Scholar 

  4. Peterfy CG (2002) Imaging of the disease process. Curr Opin Rheumatol 14:590–596

    Google Scholar 

  5. Disler DG (1997) Fat-suppressed three-dimensional spoiled gradient-recalled MR imaging: assessment of articular and physeal hyaline cartilage. Am J Roentgenol 169:1117–1123

    Google Scholar 

  6. Disler DG, McCauley TR (1998) Clinical magnetic resonance imaging of articular cartilage. Top Magn Reson Imaging 9:360–376

    Google Scholar 

  7. Kawahara Y, Uetani M, Nakahara N, Doiguchi Y, Nishiguchi M, Futagawa S, Kinoshita Y, Hayashi K (1998) Fast spin-echo MR of the articular cartilage in the osteoarthrotic knee. Correlation of MR and arthroscopic findings. Acta Radiol 39:120–125

    Google Scholar 

  8. Roemer FW, Guermazi A, Lynch JA, Peterfy CG, Nevitt MC, Webb N, Li J, Mohr A, Genant HK, Felson DT (2005) Short tau inversion recovery and proton density-weighted fat suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated extremity MRI: development of a time-efficient sequence protocol. Eur Radiol DOI 10.1007/s00330-004-2608-6

    Google Scholar 

  9. Libicher M, Ivancic M, Hoffmann V, Wenz W (2005) Early changes in experimental osteoarthritis using the Pond–Nuki dog model: technical procedure and initial results of in vivo MR imaging. Eur Radiol 15:390–394

    Google Scholar 

  10. Vande Berg BC, Lecouvet FE, Maldague B, Malghem J (2004) MR appearance of cartilage defects of the knee: preliminary results of a spiral CT arthrography-guided analysis. Eur Radiol 14:208–214

    Google Scholar 

  11. Guermazi A, Zaim S, Taouli B, Miaux Y, Peterfy CG, Genant HG (2003) MR findings in knee osteoarthritis. Eur Radiol 13:1370–1386

    Google Scholar 

  12. Graichen H, von Eisenhart-Rothe R, Vogl T, Englmeier KH, Eckstein F (2004) Quantitative assessment of cartilage status in osteoarthritis by quantitative magnetic resonance imaging: technical validation for use in analysis of cartilage volume and further morphologic parameters. Arthr Rheum 50:811–816

    Google Scholar 

  13. Burgkart R, Glaser C, Hyhlik-Durr A, Englmeier KH, Reiser M, Eckstein F (2001) Magnetic resonance imaging-based assessment of cartilage loss in severe osteoarthritis: accuracy, precision, and diagnostic value. Arthr Rheum 44:2072–2077

    Google Scholar 

  14. Eckstein F, Reiser M, Englmeier KH, Putz R (2001) In vivo morphometry and functional analysis of human articular cartilage with quantitative magnetic resonance imaging—from image to data, from data to theory. Anat Embryol (Berl) 203:147–173

    Google Scholar 

  15. Piplani MA, Disler DG, McCauley TR, Holmes TJ, Cousins JP (1996) Articular cartilage volume in the knee: semiautomated determination from three-dimensional reformations of MR images. Radiology 198:855–859

    Google Scholar 

  16. Eckstein F, Westhoff J, Sittek H, Maag KP, Haubner M, Faber S, Englmeier KH, Reiser M (1998) In vivo reproducibility of three-dimensional cartilage volume and thickness measurements with MR imaging. Am J Roentgenol 170:593–597

    Google Scholar 

  17. Cohen ZA, McCarthy DM, Kwak SD, Legrand P, Fogarasi F, Ciaccio EJ, Ateshian GA (1999) Knee cartilage topography, thickness, and contact areas from MRI: in-vitro calibration and in-vivo measurements. Osteoarthr Cartil 7:95–109

    Google Scholar 

  18. Mohr A, Priebe M, Taouli B, Grimm J, Heller M, Brossmann J (2003) Selective water excitation for faster MR imaging of articular cartilage defects: initial clinical results. Eur Radiol 13:686–689

    Google Scholar 

  19. Stammberger T, Eckstein F, Michaelis M, Englmeier KH, Reiser M (1999) Interobserver reproducibility of quantitative cartilage measurements: comparison of B-spline snakes and manual segmentation. Magn Reson Imaging 17:1033–1042

    Google Scholar 

  20. Graichen H, Springer V, Flaman T, Stammberger T, Glaser C, Englmeier KH, Reiser M, Eckstein F (2000) Validation of high-resolution water-excitation magnetic resonance imaging for quantitative assessment of thin cartilage layers. Osteoarthr Cartil 8:106–114

    Google Scholar 

  21. Kshirsagar AA, Watson PJ, Tyler JA, Hall LD (1998) Measurement of localized cartilage volume and thickness of human knee joints by computer analysis of three-dimensional magnetic resonance images. Invest Radiol 33:289–299

    Google Scholar 

  22. Cicuttini FM, Wluka AE, Forbes A, Wolfe R (2003) Comparison of tibial cartilage volume and radiologic grade of the tibiofemoral joint. Arthr Rheum 48:682–688

    Google Scholar 

  23. Uebelhart D, Malaise M, Marcolongo R, DeVathaire F, Piperno M, Mailleux E, Fioravanti A, Matoso L, Vignon E (2004) Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: a one-year, randomized, double-blind, multicenter study versus placebo. Osteoarthr Cartil 12:269–276

    Google Scholar 

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Authors and Affiliations

  1. Institute for Diagnostic and Interventional Radiology, J. W. Goethe-University Frankfurt/Main, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany

    Adel Maataoui, Nasreddin D. Abolmaali, Mohammad F. Khan, Jessen Gurung, Ralf Straub, Jun Qian & Thomas J. Vogl

  2. Department of Orthopaedic surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany

    Heiko Graichen & Stefan Hinterwimmer

  3. Institute for Bioinformatics and Statistical Analysis, Johann Wolfgang Goethe University, Frankfurt/Main, Germany

    Hanns Ackermann

Authors
  1. Adel Maataoui
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  2. Heiko Graichen
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  3. Nasreddin D. Abolmaali
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  4. Mohammad F. Khan
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  5. Jessen Gurung
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  6. Ralf Straub
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  7. Jun Qian
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  8. Stefan Hinterwimmer
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  9. Hanns Ackermann
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  10. Thomas J. Vogl
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Correspondence to Adel Maataoui.

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Maataoui, A., Graichen, H., Abolmaali, N.D. et al. Quantitative cartilage volume measurement using MRI: comparison of different evaluation techniques. Eur Radiol 15, 1550–1554 (2005). https://doi.org/10.1007/s00330-005-2744-7

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  • DOI: https://doi.org/10.1007/s00330-005-2744-7

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