Abstract
Key message
This approach is quite promising to control plant viral diseases and create synthetic networks to better understand the structure/function relationship in RNA and proteins.
Abstract
Plant viruses are obligate intracellular parasites which causes enormous losses in crop yield worldwide. These viruses replicate into infected cells by highjacking host cellular machinery. Over the last two decades, diverse approaches such as conventional breeding, transgenic approach and gene silencing strategies have been used to control RNA viruses, but escaped due to high rate of mutation. Recently, a novel CRISPR enzyme, called Cas13a, has been used engineered to confer RNA viruses resistance in plants. Here, we summarize the recent breakthrough of CRISPR/Cas13a and its applications in RNA biology.
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25 August 2021
A Correction to this paper has been published: https://doi.org/10.1007/s00299-021-02777-3
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Communicated by Neal Stewart.
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Bhushan, K. CRISPR/Cas13a targeting of RNA virus in plants. Plant Cell Rep 37, 1707–1712 (2018). https://doi.org/10.1007/s00299-018-2297-2
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DOI: https://doi.org/10.1007/s00299-018-2297-2