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Guidelines for management of rheumatic diseases in developing countries from basics to real-world situation: relevance, need, and processes for development

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Abstract

Guidelines or recommendations help to provide uniform standards in medical practice. The development of guidelines requires adherence to pre-defined norms prescribed by different international organizations such as the European League against Rheumatism (EULAR). We searched Pubmed and LILACS to identify published papers in five major rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, spondyloarthropathies, osteoarthritis, and scleroderma) from different countries based on their economic prosperity and could find a lack of published literature from most economically weaker regions. Similarly, published guidelines in these rheumatic diseases were sparse from Asia and Africa, which are economically developed to a lesser extent than other regions of the world. Considering differing economic realities driving patient care in different regions of the world, unique challenges in certain geographic areas such as musculoskeletal manifestations of infectious diseases like leprosy and tuberculosis, as well as distinct risk of malignancies and other comorbid conditions, National Rheumatology societies should work towards developing more guidelines for rheumatic diseases from regions such as Asia and Africa, while following strictly the prescribed norms for the same. With a paucity of guidelines for such regions currently, an alternative (although less preferable) suggestion would be that major international societies, whose guidelines are widely read and followed the world over, should consider inputs from experts from diverse regions of the world while developing these guidelines.

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Abbreviations

ACR:

American College of Rheumatology

AGREE:

Appraisal of Guidelines for Research and Evaluation

ALNN:

Asian Lupus Nephritis Network

APLAR:

Asia Pacific League against Rheumatism

bDMARDs:

Biologic disease-modifying anti-rheumatic drugs

cDMARDS:

Conventional disease-modifying anti-rheumatic drugs

CNI:

Calcineurin inhibitors

ERA–EDTA:

European Renal Association–European Dialysis and Transplant Association

EULAR:

European League against Rheumatism

GRADE:

Grading of recommendations, assessment, development and evaluations

GRADEpro:

GRADE profiler

GDP:

Gross domestic product

GNI:

Gross national income

LILACS:

Literatura Latino Americana em Ciências da Saúde

NICE:

National Institute of Clinical Excellence

PADI:

Peptidyl arginine deiminase

PICO:

Patient intervention comparator outcome

PRISMA:

Preferred reporting standards for systematic reviews and meta-analysis

PTPN22:

Protein tyrosine phosphatase 22

SOP:

Standard operating procedure

WHO:

World Health Organization

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Authors and Affiliations

Authors

Contributions

The conception and design of the study, or acquisition of data, or analysis and interpretation of data—DPM, AS, VA. Drafting the article—DPM; revising it critically for important intellectual content—AS, VA. Final approval of the version to be submitted—DPM, AS, VA. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved—DPM, AS, VA.

Corresponding author

Correspondence to Durga Prasanna Misra.

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Conflict of interest

Durga Prasanna Misra declares that he has no conflict of interest, including no relationship with pharmaceutical companies. Aman Sharma declares that he has no conflict of interest, including no relationship with pharmaceutical companies. Vikas Agarwal declares that he has no conflict of interest, including no relationship with pharmaceutical companies.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Misra, D.P., Sharma, A. & Agarwal, V. Guidelines for management of rheumatic diseases in developing countries from basics to real-world situation: relevance, need, and processes for development. Rheumatol Int 38, 549–556 (2018). https://doi.org/10.1007/s00296-018-3996-2

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