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Signal recognition particle (SRP) positive myositis in a patient with cryptogenic organizing pneumonia (COP)

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Abstract

We report of a 46-year-old female patient with cryptogen organizing pneumonia preceeding the rare SRP positive necrotising myositis without cardiac involvement and no sign of dysphagia. Myositis showed full regression without oral immune suppression but with extracorporeal treatment, performed as a combined therapy of plasmaexchange and immunoadsorption. After 33-month of treatment, anti-SRP antibodies were not detectable any more.

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Acknowledgments

We want to thank Dr. Hilde Veterale and Prof. Gerhard Mostbeck from the Department of Radiology, Wilhelminenspital for their help.

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Authors and Affiliations

  1. Department of Pneumonology, Medical University of Vienna, Wilhelminenspital, Vienna, Austria

    Felix Wantke, Meinhard Kneussl & Marianne Hubner

  2. Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria

    Kurt Derfler & Sabine Schmaldienst

  3. Department of Neurology, Medical University of Vienna, Wilhelminenspital, Vienna, Austria

    Thomas Brücke

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  1. Felix Wantke
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  2. Meinhard Kneussl
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  3. Marianne Hubner
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  4. Kurt Derfler
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  5. Thomas Brücke
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  6. Sabine Schmaldienst
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Correspondence to Felix Wantke.

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Wantke, F., Kneussl, M., Hubner, M. et al. Signal recognition particle (SRP) positive myositis in a patient with cryptogenic organizing pneumonia (COP). Rheumatol Int 30, 1361–1365 (2010). https://doi.org/10.1007/s00296-009-1059-4

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  • DOI: https://doi.org/10.1007/s00296-009-1059-4

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