Sexual problems in male vs. female non-Hodgkin lymphoma survivors: prevalence, correlates, and associations with health-related quality of life
- 233 Downloads
The objective of this study was to examine the prevalence and factors associated with sexual problems and their relationship to health-related quality of life (HRQOL) in male and female non-Hodgkin lymphoma (NHL) survivors. In this cross-sectional study, 738 NHL survivors (425 men and 313 women; mean time since diagnosis, 6.2 years) in South Korea completed the six-item instrument of adult sexual behavior used by the National Health and Social Life Survey in the United States. HRQOL was measured by two subscales of the EORTC QLQ-C30. Sexual problems were reported by a greater proportion of women (range, 31.9 to 64.4%) than men (range, 23.3 to 49.1%). Among four items common to both sexes, three (lacking interest in sex, unable to achieve orgasm, sex not pleasurable) were significantly more prevalent in women. Significant factors associated with multiple sexual problems in men were older age and being unemployed; in women, they were marital status and comorbidity. Lastly, more significant associations between sexual problems and HRQOL were observed in men than in women. Male and female NHL survivors differ in the prevalence of sexual problems and the factors associated with them as well as their associations with HRQOL. These findings can be used to develop sex-specific interventions to improve sexual function in this population.
KeywordsSex Lymphoma Sexual problems Survivors
This paper was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant number 2016R1D1A1B04932171).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
- 14.Greaves P, Sarker SJ, Chowdhury K, Johnson R, Matthews J, Matthews R, Smith M, Korszun A, Gribben JG, Lister TA (2014) Fertility and sexual function in long-term survivors of haematological malignancy: using patient-reported outcome measures to assess a neglected area of need in the late effects clinic. Br J Haematol 164:526–535. doi: 10.1111/bjh.12651 CrossRefPubMedGoogle Scholar
- 16.Kornblith AB, Anderson J, Cella DF, Tross S, Zuckerman E, Cherin E, Henderson ES, Weiss RB, Cooper MR, Silver RT (1990) Quality of life assessment of Hodgkin’s disease survivors: a model for cooperative clinical trials. Oncology (Williston Park) 4:93–101 discussion 104Google Scholar
- 21.Laumann EO, Gagnon JH, Michael RT, Michaels S (1994) The social organization of sexuality: sexual practices in the United States. University of Chicago Press, ChicagoGoogle Scholar
- 24.Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85:365–376CrossRefPubMedGoogle Scholar
- 28.Hewitt M, Greenfield S, Stovall E (2006) From cancer patients to cancer survivors: lost in transition. National Academy Press, Washington DCGoogle Scholar
- 31.Behringer K, Müller H, Görgen H, Flechtner HH, Brillant C, Halbsguth TV, Thielen I, Eichenauer DA, Schober T, Nisters-Backes H, Fuchs M, Engert A, Borchmann P (2013) Sexual quality of life in Hodgkin lymphoma: a longitudinal analysis by the German Hodgkin Study Group. Br J Cancer 108:49–57. doi: 10.1038/bjc.2012.550 PubMedPubMedCentralGoogle Scholar
- 32.American Cancer Society (2016) http://www.cancer.org/treatment/treatmentsandsideeffects/physicalsideeffects/sexualsideeffectsinmen/sexualityfortheman/sexuality-for-men-with-cancer-erections-and-chemo. Accessed 28 Dec 2016
- 33.Cancer Care (2016) http://chemocare.com/chemotherapy/side-effects/impotence.aspx. Accessed 29 Dec 2016