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Direct Injection of Blood Products Versus Gelatin Sponge as a Technique for Local Hemostasis

  • Clinical Investigation
  • Published:
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Abstract

Purpose

To provide a method of reducing risk of minimally invasive procedures on patients with abnormal hemostasis and evaluate efficacy of direct fresh frozen plasma injection through a procedure needle tract compared to Gelfoam (gelatin sponge) administration.

Materials and Methods

Eighty patients with elevated international standardized ratio (INR) undergoing minimally invasive procedures using imaging guidance were selected retrospectively. Forty patients had received Gelfoam as a means of tract embolization during the procedure. The other 40 received local fresh frozen plasma (FFP) through the needle tract. The number of complications and clinically significant bleeding events were recorded. A threshold of 30 cc of blood loss after a procedure was used to identify excess bleeding.

Results

No patients experienced clinically significant bleeding after administration of FFP. Five patients experienced postoperative drops in hemoglobin or hematomas after administration of Gelfoam.

Conclusion

Local injection of blood products can reduce postprocedure bleeding in patients undergoing minimally invasive procedures and provides a safe alternative to the use of synthetic fibrin plugs.

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Conflicts of interest

All authors have no financial disclosures to report. There was no funding for this research project or manuscript preparation. There are no conflicts of interest to report.

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Author notes

  1. Shiraz Rahim

    Present address: , 11100 Euclid Ave, Cleveland, OH, 44106, USA

Authors and Affiliations

  1. Department of Radiology, University Hospitals Case Medical Center, Cleveland, OH, USA

    John Haaga & Shiraz Rahim

Authors
  1. John Haaga
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  2. Shiraz Rahim
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Correspondence to Shiraz Rahim.

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Haaga, J., Rahim, S. Direct Injection of Blood Products Versus Gelatin Sponge as a Technique for Local Hemostasis. Cardiovasc Intervent Radiol 40, 231–235 (2017). https://doi.org/10.1007/s00270-016-1494-z

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  • DOI: https://doi.org/10.1007/s00270-016-1494-z

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