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Analysis of Growth, Nutritional Status and Hospital Visitation Scores Associated with Reflux After Nissen Fundoplication in Neurologically Impaired Children with Gastroesophageal Reflux

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Abstract

Background

Neurologically impaired children (NIC) often experience swallowing difficulties and gastroesophageal reflux disease (GERD). Although these conditions could place children in a state of poor nutritional status and prevent them from thriving, there is insufficient research evaluating growth and nutritional status following fundoplication in these patients.

Method

This is a retrospective study of patients who were neurologically impaired and underwent Nissen fundoplication between April 2001 and March 2015. Seventy-six patients were enrolled, and the follow-up period was 12 months or longer. Growth was measured by the change in body weight and height. Nutritional status was measured by the change in body mass index, serum albumin and protein level.

Results

Median age at operation was 1.85 years old, and median body weight was 10 kg. The respective Z scores for weight and height showed significant improvements after 1 year since the operation compared to 1 year within the operation (−2.42 ± 2.19 vs. −1.31 ± 1.96, P < 0.001) (−1.6 ± 2.16 vs. −1.05 ± 1.69, P = 0.002). The respective Z scores for body mass index, albumin and protein also showed improvements after 1 year since the operation compared to 1 year within the operation (−2.07 ± 2.99 vs. −0.89 ± 2.1, P < 0.001) (3.55 ± 0.48 vs. 3.86 ± 0.45, P < 0.001) (6.22 ± 0.76 vs. 6.65 ± 0.51, P < 0.001). Hospital visitation scores associated with reflux were significantly lower after the operation (4.1 ± 3.43 vs. 1.18 ± 1.67, P < 0.001).

Conclusions

In summary, after Nissen fundoplication in NIC with GER, growth and nutritional status improved significantly. Also, hospital visitation scores associated with reflux decreased after the operation.

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Authors and Affiliations

  1. Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

    Chaeyoun Oh, Joong Kee Youn, Ji-Won Han, Hyun-Young Kim & Sung-Eun Jung

  2. Department of Pediatric Surgery, Children’s Hospital, Seoul National University, 101 Daehang-ro, Yeongeon-dong, Jongno-gu, Seoul, 03080, Korea

    Hyun-Young Kim

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  1. Chaeyoun Oh
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Correspondence to Hyun-Young Kim.

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Oh, C., Youn, J.K., Han, JW. et al. Analysis of Growth, Nutritional Status and Hospital Visitation Scores Associated with Reflux After Nissen Fundoplication in Neurologically Impaired Children with Gastroesophageal Reflux. World J Surg 42, 1463–1468 (2018). https://doi.org/10.1007/s00268-017-4276-0

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