Longitudinal Analysis of Superficial Midfacial Fat Volumes Over a 10-Year Period

Original Article Facial Surgery
  • 16 Downloads

Abstract

Background

Volumetric changes to facial fat that occur with aging remain poorly understood. The aim of this study was to evaluate for longitudinal changes to midfacial fat volumes in a group of individuals.

Methods

We conducted a retrospective longitudinal study of adult subjects who underwent multiple facial computed tomographic (CT) scans timed at least 8 years apart. Subjects who underwent facial surgery or suffered facial trauma were excluded. Facial CT scans were analyzed, and superficial cheek fat volumes were measured and compared to track changes that occurred with aging.

Results

Fourteen subjects were included in our analysis of facial aging (5 male, 9 female; mean initial age 50.9 years; mean final age 60.4 years). In the right superficial cheek there was an increase in mean (SD) superficial fat volume from 10.33 (2.01) to 10.50 (1.80) cc, which was not statistically significant (P = 0.75). Similar results were observed in the left cheek. There were no statistically significant longitudinal changes to caudal, middle, or cephalad subdivisions of bilateral superficial cheek fat. A simple linear regression was performed to predict superficial cheek fat pad volume based on age which did not reach statistical significance (P = 0.31), with an R2 of 0.039.

Conclusions

This study is the first to quantitatively assess for longitudinal changes to midfacial fat in a group of individuals. Superficial cheek fat remained stable as subjects aged from approximately 50 to 60 years old, with no change in total volume or redistribution within a radiographically defined compartment.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Keywords

Aging Cheek Fat Face Facial rejuvenation Computed tomography 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Wan D, Amirlak B, Rohrich R, Davis K (2013) The clinical importance of the fat compartments in midfacial aging. Plast Reconstr Surg Glob Open 1:e92CrossRefPubMedGoogle Scholar
  2. 2.
    Lambros V (2007) Observations on periorbital and midface aging. Plast Reconstr Surg 120:1367–1376 (discussion 1377) CrossRefPubMedGoogle Scholar
  3. 3.
    Donofrio LM (2000) Fat distribution: a morphologic study of the aging face. Dermatol Surg 26:1107–1112CrossRefPubMedGoogle Scholar
  4. 4.
    Gosain AK, Klein MH, Sudhakar PV, Prost RW (2005) A volumetric analysis of soft-tissue changes in the aging midface using high-resolution MRI: implications for facial rejuvenation. Plast Reconstr Surg 115:1143–1152 (discussion 1153–1145) CrossRefPubMedGoogle Scholar
  5. 5.
    Gierloff M, Stohring C, Buder T, Gassling V, Acil Y, Wiltfang J (2012) Aging changes of the midfacial fat compartments: a computed tomographic study. Plast Reconstr Surg 129:263–273CrossRefPubMedGoogle Scholar
  6. 6.
    Rohrich RJ, Pessa JE (2007) The fat compartments of the face: anatomy and clinical implications for cosmetic surgery. Plast Reconstr Surg 119:2219–2227 (discussion 2228–2231) CrossRefPubMedGoogle Scholar
  7. 7.
    Schaverien MV, Pessa JE, Rohrich RJ (2009) Vascularized membranes determine the anatomical boundaries of the subcutaneous fat compartments. Plast Reconstr Surg 123:695–700CrossRefPubMedGoogle Scholar
  8. 8.
    Rohrich RJ, Pessa JE, Ristow B (2008) The youthful cheek and the deep medial fat compartment. Plast Reconstr Surg 121:2107–2112CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery 2018

Authors and Affiliations

  • Jacob Tower
    • 1
  • Kimberly Seifert
    • 2
  • Boris Paskhover
    • 3
  1. 1.Section of Otolaryngology, Department of SurgeryYale School of MedicineNew HavenUSA
  2. 2.Department of Radiology and Biomedical ImagingYale School of MedicineNew HavenUSA
  3. 3.Department of Otolaryngology – Head and Neck SurgeryRutgers New Jersey Medical SchoolNewarkUSA

Personalised recommendations