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International Orthopaedics

, Volume 42, Issue 7, pp 1517–1525 | Cite as

Quality of life of patients with osteonecrosis of the femoral head: a multicentre study

  • Yuko Uesugi
  • Takashi Sakai
  • Taisuke Seki
  • Shinya Hayashi
  • Junichi Nakamura
  • Yutaka Inaba
  • Daisuke Takahashi
  • Kan Sasaki
  • Goro Motomura
  • Naohiko Mashima
  • Tamon Kabata
  • Akihiro Sudo
  • Tetsuya Jinno
  • Wataru Ando
  • Satoshi Nagoya
  • Kengo Yamamoto
  • Satoshi Nakasone
  • Hiroshi Ito
  • Takuaki Yamamoto
  • Nobuhiko Sugano
Original Paper

Abstract

Purpose

Quality-of-life (QOL) assessments in patients with osteonecrosis of the femoral head (ONFH) have rarely been reported. This multicentre study aimed to elucidate the relationship between disease severity, including necrotic lesion type and radiological staging, and QOL, as well as between patients’ characteristics and QOL.

Methods

Two hundred seventy-four patients with ONFH (108 females, 166 males; median age, 46 years) were asked to complete self-assessment QOL questionnaires including the Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire, Oxford Hip Score, and SF-12v2.

Results

Patients with large necrotic lesion type or collapsed ONFH had low QOL scores. Among patients with non-collapsed lesions, patients with alcohol-associated ONFH had lower QOL scores than those with steroid-associated ONFH, those with bilateral ONFH had lower mental scores, and male patients had worse social condition scores. Among patients with collapsed lesions, middle-aged patients exhibited lower mental QOL, and a strong correlation was observed between social activity and mental health.

Conclusion

Collapsed ONFH was associated with low QOL scores. Among patients with non-collapsed lesions, alcohol-associated ONFH, bilateral disease, and male sex were linked to low QOL scores.

Keywords

Osteonecrosis of the femoral head (ONFH) Quality of life (QOL) Radiological stage Steroid-associated Alcohol-associated 

Abbreviations

JIC

Japanese Investigating Committee

JHEQ

Japanese Orthopaedic Association Hip-Disease Evaluation Questionnaire

OHS

Oxford Hip Score

PCS

Physical component summary

MCS

Mental component summary

RCS

Role/social component summary

Notes

Acknowledgements

We thank Prof Wakaba Fukushima and Mr. Kazuya Ito for their helpful advices. We also thank Drs Hiromasa Tanino, Toshiyuki Tateiwa, Yusuke Kubo, Daisuke Inoue, Satoshi Kubota, Hiroyuki Ike, Yohei Naito, Masaki Takao, and Hidetoshi Hamada for their helpful support.

Funding information

The principal investigator (NS) of the Japanese Investigation Committee under the auspices of the Ministry of Health Labour and Welfare received a research grant from the Ministry of Health and Welfare of Japan (Research on Measures for Intractable Diseases).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

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Copyright information

© SICOT aisbl 2018

Authors and Affiliations

  • Yuko Uesugi
    • 1
  • Takashi Sakai
    • 2
  • Taisuke Seki
    • 3
  • Shinya Hayashi
    • 4
  • Junichi Nakamura
    • 5
  • Yutaka Inaba
    • 6
  • Daisuke Takahashi
    • 7
  • Kan Sasaki
    • 8
  • Goro Motomura
    • 9
  • Naohiko Mashima
    • 10
  • Tamon Kabata
    • 11
  • Akihiro Sudo
    • 12
  • Tetsuya Jinno
    • 13
  • Wataru Ando
    • 14
  • Satoshi Nagoya
    • 15
  • Kengo Yamamoto
    • 16
  • Satoshi Nakasone
    • 17
  • Hiroshi Ito
    • 18
  • Takuaki Yamamoto
    • 19
  • Nobuhiko Sugano
    • 20
  1. 1.Department of International Health, Graduate School of Health ScienceKobe UniversityKobeJapan
  2. 2.Department of Orthopaedic Surgery, Graduate School of MedicineOsaka UniversitySuitaJapan
  3. 3.Department of Orthopaedic Surgery, Graduate School of MedicineNagoya UniversityNagoyaJapan
  4. 4.Department of Orthopaedic Surgery, Graduate School of MedicineKobe UniversityKobeJapan
  5. 5.Department of Orthopaedic Surgery, Graduate School of MedicineChiba UniversityChibaJapan
  6. 6.Department of Orthopaedic Surgery, Graduate School of MedicineYokohama City UniversityYokohamaJapan
  7. 7.Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporoJapan
  8. 8.Department of Orthopaedic Surgery, Faculty of MedicineYamagata UniversityYamagataJapan
  9. 9.Department of Orthopaedic Surgery, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan
  10. 10.Department of Orthopaedic Surgery, Graduate School of MedicineEhime UniversityToonJapan
  11. 11.Department of Orthopaedic Surgery, Graduate School of Medical scienceKanazawa UniversityKanazawaJapan
  12. 12.Department of Orthopaedic Surgery, Graduate School of MedicineMie UniversityTsuJapan
  13. 13.Department of Orthopaedic Surgery, Graduate School of MedicineTokyo Medical and Dental UniversityBunkyo-KuJapan
  14. 14.Department of Orthopaedic SurgeryKansai-Rosai HospitalAmagasakiJapan
  15. 15.Department of Orthopaedic SurgerySapporo Medical UniversitySapporoJapan
  16. 16.Department of Orthopaedic Surgery, School of MedicineTokyo Medical UniversityTokyoJapan
  17. 17.Department of Orthopaedic Surgery, Graduate School of MedicineUniversity of the RyukusNishiharaJapan
  18. 18.Department of Orthopaedic Surgery, School of MedicineAsahikawa Medical UniversityAsahikawaJapan
  19. 19.Department of Orthopaedic Surgery, Faculty of MedicineFukuoka UniversityFukuokaJapan
  20. 20.Department of Orthopaedic Medical Engineering, Graduate School of MedicineOsaka UniversitySuitaJapan

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