Treatment of the aneurysmal bone cyst by percutaneous intracystic sclerotherapy using ethanol ninety five percent in children
- 65 Downloads
Aneurysmal bone cyst (ABC) is a benign intraosseous lesion filled with blood that can determine a blowout distension of the bone. The purpose of this study is to evaluate the efficacy of sclerotherapy by percutaneous intralesional administration of ethanol 96% for the treatment of this pathology in paediatric patients.
The retrospective study includes 17 paediatric patients with ABC who were treated by repeated intracystic injection with ethanol 96%, 1 ml/kg, in our clinic between December 2015 and July 2017. Fluoroscopic guidance was used to inject the cyst with contrast agent. The mean follow-up period was 11 months.
Results and discussion
All cysts are healed or are in the healing process. The mean age was 11 years old. Seven patients needed three repeated injections and ten patients needed two injections until healing. We observed a mean reduction in the size of the lesions, measured on plain X-rays, of 68%. The complications that were observed included the following: dizziness after injection, skin pigmentation at the injection site, local inflammatory reaction, and pain after injection. The current study approves the importance of this minimally invasive treatment with no recurrence after a follow-up of 19 months. The healing rate was 100%. A limitation of this study consists in the small number of patients.
Sclerotherapy with ethanol 96% is a useful method for the treatment of ABC. It is a minimally invasive method, with no major complications, which lowers the risks of open surgical intervention and has a good rate of success.
KeywordsBone tumor Aneurysmal bone cyst Sclerotherapy Bone cyst Ethanol
Compliance with ethical standards
Conflict of interests
The authors declare that they have no conflict of interests.
This article does have the department’s ethical committee approval for this retrospective study.
- 1.Olvi LG, Lembo GM, Velan O, Santini-Araujo E (2015) Aneurysmal Bone Cyst. In: Santini-Araujo E, Kalil R, Bertoni F, Park YK (eds) Tumors and Tumor-Like Lesions of Bone. Springer, LondonGoogle Scholar
- 2.Folpe AL, Inwards CY (2010) Bone and soft tissue pathology, 1st edn. bone tumors of miscellaneous type of uncertain lineage. London, Elsevier, p 428–433Google Scholar
- 3.Unni KK, Inwards CY (2010) Dahlin’s bone tumors: general aspects and data on 10,165 cases, 6th edn. Aneurysmal Bone Cyst. Philadelphia, Lippincott Williams & Wilkins, p 333–343Google Scholar
- 4.Nielsen GP, Fletcher JA, Oliveira AM (2013) WHO classification of tumors of soft tissue and bone aneurysmal bone cyst. Aneurysmal Bone Cyst. Lyon, IARC Press pp 348–349Google Scholar
- 5.Mulder JD, Schutte HE, Kroon HM, Taconis WK (1993) Radiologic atlas of bone tumors: the diagnosis of bone tumors. Amsterdam , Elsevier, p 9–46Google Scholar
- 6.Mulder JD, Schutte HE, Kroon HM, Taconis WK (1993) Radiologic atlas of bone tumors, aneurysmal bone cyst. Amsterdam, Elsevier, p 557–577Google Scholar
- 12.Ulici A, Sterian AG, Tevanov I, Carp M, Dusca A, Cosma D (2018) Aggressive development of an aneurysmal bone cyst of the proximal femur in a paediatric patient: a case report. J Int Med Res 46(1):538–545. https://doi.org/10.1177/0300060517722244
- 16.Rossi G, Mavrogenis AF, Facchini G, Bartalena T, Rimondi E, Renzulli M, Errani C (2016) How effective is embolization with N-2-butyl-cyanoacrylate for aneurysmal bone cysts? Int Orthop:1–8. https://doi.org/10.1007/s00264-016-3364-3
- 19.Lambot-Juhan K, Pannier S, Grévent D, Péjin Z, Breton S, Berteloot L, Emond-Gonsard S, Boddaert N, Glorion C, Brunelle F (2012) Primary aneurysmal bone cysts in children: percutaneous sclerotherapy with absolute alcohol and proposal of a vascular classification. Pediatr Radiol 42(5):599–605. https://doi.org/10.1007/s00247-011-2312-z CrossRefPubMedGoogle Scholar