Abdominal Radiology

, Volume 43, Issue 11, pp 2923–2927 | Cite as

New intra-abdominal mass after operation for colorectal cancer: desmoid tumor versus peritoneal seeding

  • Ji Hoon Lee
  • Kyoung Doo SongEmail author
  • Dong Ik Cha
  • Seung Hyup Hyun



To identify differential clinical and imaging findings between intra-abdominal desmoid tumors and peritoneal seeding that developed after surgery for colorectal cancer.


8 patients (9 desmoid tumors) and 11 patients (13 peritoneal seeding masses) were enrolled in our retrospective study. Patients with three or more tumors were excluded. Clinical findings including location of initial tumors, type of surgery, T- and N-stages of initial tumors, time interval between initial surgery and development of intra-abdominal tumors, and level of carcinoembryonic antigen (CEA) were evaluated. Imaging findings of intra-abdominal tumors including size, number, growth rate, location, shape, homogeneity, relative enhancement, and maximum standardized uptake value were evaluated. The Mann–Whitney U test and Fisher’s exact test were used to compare clinical and imaging findings between desmoid tumors and peritoneal seeding.


In patients with a desmoid tumor, initial T-stage, initial N-stage, and level of CEA at the time of surgery for intra-abdominal tumor were lower than in patients with peritoneal seeding (p = 0.027, p = 0.033, and p = 0.017). The desmoid tumors were frequently located in the small bowel mesentery (p = 0.018) and were larger at detection (p = 0.041). Round or ovoid shapes on CT images were more frequently observed with the desmoid tumors (p = 0.035).


Stage of colorectal cancer, CEA level, and location, size, and shape of new intra-abdominal tumors can be helpful for differentiating between intra-abdominal desmoid tumors and peritoneal seeding in patients with a history of colorectal cancer surgery.


Colorectal cancer Desmoid tumor Peritoneal seeding Clinical finding Imaging finding 


  1. 1.
    Reitamo JJ, Hayry P, Nykyri E, Saxen E (1982) The desmoid tumor. I. Incidence, sex-, age- and anatomical distribution in the Finnish population. Am J Clin Pathol 77:665–673CrossRefGoogle Scholar
  2. 2.
    Sheth S, Horton KM, Garland MR, Fishman EK (2003) Mesenteric neoplasms: CT appearances of primary and secondary tumors and differential diagnosis. Radiographics 23:457–473 (quiz 535–456)CrossRefGoogle Scholar
  3. 3.
    Mizuno R, Akiyoshi T, Kuroyanagi H, et al. (2011) Intra-abdominal desmoid tumor mimicking locoregional recurrence after colectomy in a patient with sporadic colon cancer: report of a case. Surg Today 41:730–732CrossRefGoogle Scholar
  4. 4.
    Das S, Subhashini J, Isiah R, Kurian S (2012) Mesenteric fibromatosis mimicking metastasis: a case report and review of literature. J Gastrointest Cancer 43(Suppl 1):S73–76CrossRefGoogle Scholar
  5. 5.
    Nakanishi K, Shida D, Tsukamoto S, et al. (2017) Multiple rapidly growing desmoid tumors that were difficult to distinguish from recurrence of rectal cancer. World J Surg Oncol 15:180CrossRefGoogle Scholar
  6. 6.
    Salas S, Dufresne A, Bui B, et al. (2011) Prognostic factors influencing progression-free survival determined from a series of sporadic desmoid tumors: a wait-and-see policy according to tumor presentation. J Clin Oncol 29:3553–3558CrossRefGoogle Scholar
  7. 7.
    Tsikitis VL, Larson DW, Huebner M, Lohse CM, Thompson PA (2014) Predictors of recurrence free survival for patients with stage II and III colon cancer. BMC Cancer 14:336CrossRefGoogle Scholar
  8. 8.
    Ryuk JP, Choi GS, Park JS, et al. (2014) Predictive factors and the prognosis of recurrence of colorectal cancer within 2 years after curative resection. Ann Surg Treat Res 86:143–151CrossRefGoogle Scholar
  9. 9.
    Bast RC Jr, Ravdin P, Hayes DF, et al. (2001) 2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19:1865–1878CrossRefGoogle Scholar
  10. 10.
    Chaudhary P (2014) Mesenteric fibromatosis. Int J Colorectal Dis 29:1445–1451CrossRefGoogle Scholar
  11. 11.
    Ko SF, Lin JW, Ng SH, et al. (2006) Spontaneous isolated mesenteric fibromatosis: sonographic and computed tomographic findings with pathologic correlation. Ultrasound Med Biol 32:1141–1149CrossRefGoogle Scholar
  12. 12.
    Healy JC (2001) Detection of peritoneal metastases. Cancer Imaging 1:4–12CrossRefGoogle Scholar
  13. 13.
    Brooks AP, Reznek RH, Nugent K, et al. (1994) CT appearances of desmoid tumours in familial adenomatous polyposis: further observations. Clin Radiol 49:601–607CrossRefGoogle Scholar
  14. 14.
    Zhu H, Chen H, Zhang S, Peng W (2013) Intra-abdominal fibromatosis: differentiation from gastrointestinal stromal tumour based on biphasic contrast-enhanced CT findings. Clin Radiol 68:1133–1139CrossRefGoogle Scholar
  15. 15.
    Kasper B, Dimitrakopoulou-Strauss A, Strauss LG, Hohenberger P (2010) Positron emission tomography in patients with aggressive fibromatosis/desmoid tumours undergoing therapy with imatinib. Eur J Nucl Med Mol Imaging 37:1876–1882CrossRefGoogle Scholar
  16. 16.
    Basu S, Nair N, Banavali S (2007) Uptake characteristics of fluorodeoxyglucose (FDG) in deep fibromatosis and abdominal desmoids: potential clinical role of FDG-PET in the management. Br J Radiol 80:750–756CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Radiology and Center for Imaging Science, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulRepublic of Korea
  2. 2.Department of Nuclear Medicine, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulRepublic of Korea

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