Mucinous appendiceal neoplasms: pathologic classification, clinical implications, imaging spectrum and mimics
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Mucinous appendiceal neoplasms are uncommon, but important to recognize with imaging due to malignant potential. Peritoneal seeding and pseudomyxoma peritonei can occur with both frankly malignant as well as low-grade appendiceal neoplasms. Prospective imaging identification of potential appendiceal neoplasm is paramount to clinical/surgical management. When a mucinous appendiceal neoplasm is suspected, a right hemicolectomy with lymph node dissection is the preferred surgical management. Unfortunately, accurate preoperative diagnosis can be challenging due to a wide range of clinical presentations and overlapping imaging appearances of appendiceal neoplasms with benign entities. Using the 2010 World Health Organization (WHO) pathologic classification as a framework, we provide a comprehensive multi-modality pictorial essay detailing the broad array of imaging findings of mucinous appendiceal neoplasms and common imaging mimics.
KeywordsMucocele Appendix Pseudomyxoma peritonei Neoplasm
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Conflict of interest
All three authors declare that they have no conflicts of interest. No grants or funding involved in this project.
The study is a retrospective review of the medical record and is compliant with Henry Ford Hospital’s Institutional Review Board guidelines (IRB# 7550). This article does not contain studies with human or animal participants performed by any of the authors.
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