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Reply: Interim FDG-PET/CT in primary mediastinal diffuse large B-cell lymphoma: really almost useless procedure?

  • Julien Lazarovici
  • Marie Terroir-Cassou-Mounat
  • David Ghez
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  • 170 Downloads

Dear Sir,

We read the comments by Procházka et al. on our article. The purpose of our work was to assess the positive predictive value of interim PET/CT, which was thought to be poor in PMBCL, examining whether there was a correlation between PET/CT results and histological examination. They raised several issues on the reliability of our assessment. Our answers are as follows:
  1. 1.

    The results reported in this study were obtained over a period of 8 years, during which two different PET/CT devices were used. As the certification procedure is effective in the department only since the commissioning of the Discovery PET/CT, Procházka et al. point out that the images were not obtained under the same conditions. Although this remark is relevant, this point does not seem very critical to us since the initial analysis of the images was performed on a visual basis. This non-quantitative approach is less sensitive to the intrinsic performances of the device, especially since the PSF recovery...

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© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Julien Lazarovici
    • 1
  • Marie Terroir-Cassou-Mounat
    • 2
  • David Ghez
    • 1
  1. 1.Department of Hematology Gustave Roussy and Université Paris SaclayVillejuifFrance
  2. 2.Department of Nuclear Medicine and Endocrine OncologyGustave Roussy and Université Paris SaclayVillejuifFrance

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