68Ga-Pentixafor PET/CT demonstrating higher CXCR4 density in small cell lung carcinoma than in non-small cell variant

  • Ankit Watts
  • Baljinder Singh
  • Rajender Basher
  • Harmandeep Singh
  • Amanjit Bal
  • Rakesh Kapoor
  • Sunil K. Arora
  • Hans J. Wester
  • B. R. Mittal
  • D. Behera
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References

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    Wald O, Shapira OM, Izhar U. CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential. Theranostics. 2013;3:26–33.CrossRefPubMedPubMedCentralGoogle Scholar
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    Demmer O, Gourni E, Schumacher U, Kessler H, Wester HJ. PET imaging of CXCR4 receptors in cancer by a new optimized ligand. Chem Med Chem. 2011;4(6):1789–91.CrossRefGoogle Scholar
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    Lapa C, Lückerath K, Rudelius M, Schmid JS, Schoene A, Schirbel A, et al. [68Ga]Pentixafor-PET/CT for imaging of chemokine receptor 4 expression in small cell lung cancer–initial experience. Oncotarget. 2016;7:9288–95.PubMedPubMedCentralGoogle Scholar
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    Vag T, Gerngross C, Herhaus P, Eiber M, Philipp-Abbrederis K, Graner FP, et al. First experience with chemokine receptor CXCR4-targeted PET imaging of patients with solid cancers. J Nucl Med. 2016;57:741–6.CrossRefPubMedGoogle Scholar
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    Herrmann K, Schottelius M, Lapa C, Osl T, Poschenrieder A, Hänscheid H, et al. First-in-human experience of CXCR4-directed endoradiotherapy with 177Lu- and 90Y-labeled pentixather in advanced-stage multiple myeloma with extensive intra- and extramedullary disease. J Nucl Med. 2016;57:248–51.CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Ankit Watts
    • 1
  • Baljinder Singh
    • 1
  • Rajender Basher
    • 1
  • Harmandeep Singh
    • 1
  • Amanjit Bal
    • 1
  • Rakesh Kapoor
    • 1
  • Sunil K. Arora
    • 1
  • Hans J. Wester
    • 1
  • B. R. Mittal
    • 1
  • D. Behera
    • 1
  1. 1.Postgraduate Institute of Medical Education and ResearchChandigarhIndia

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