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Skeletal Radiology

, Volume 47, Issue 5, pp 703–709 | Cite as

Atypical lipomatous tumor of the hand with transformation to dedifferentiated liposarcoma: a case report

  • Daniel C. Ramirez
  • Sinchun Hwang
  • Edward A. Athanasian
  • Lu Wang
  • Meera Hameed
Case Report

Abstract

Atypical lipomatous tumor/well-differentiated liposarcoma is the most common sarcoma of soft tissue in adults. We describe the clinical, radiologic, and pathologic features of an atypical lipomatous tumor arising within the soft tissue of the left hand of a 68-year-old female that underwent transformation to dedifferentiated liposarcoma and eventually metastasized. At initial presentation, imaging demonstrated an extensively calcified fatty soft tissue mass with displacement of the digits. Following biopsy and staged debulking, the patient subsequently developed local recurrence, dedifferentiation, and widespread metastases to the lungs, pancreas, bone, and soft tissues. To our knowledge, this is the first case of a cytogenetically proven atypical lipomatous tumor of the hand that has undergone dedifferentiation with widespread metastases.

Keywords

Liposarcoma Hand Dedifferentiated CT MRI PET Metastases 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© ISS 2017

Authors and Affiliations

  • Daniel C. Ramirez
    • 1
    • 2
  • Sinchun Hwang
    • 3
  • Edward A. Athanasian
    • 4
  • Lu Wang
    • 1
  • Meera Hameed
    • 1
  1. 1.Department of PathologyMemorial Sloan Kettering Cancer CenterNew YorkUSA
  2. 2.Department of Pathology and Laboratory MedicineHospital For Special SurgeryNew YorkUSA
  3. 3.Department of RadiologyMemorial Sloan Kettering Cancer CenterNew YorkUSA
  4. 4.Department of SurgeryMemorial Sloan Kettering Cancer CenterNew YorkUSA

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